2-[Ethyl(prop-2-yn-1-yl)amino]ethanol

Base Information

• Chemical Name: 2-[Ethyl(prop-2-yn-1-yl)amino]ethanol
• CAS No.: 13105-73-2
• Molecular Formula: C7H13NO
• Molecular Weight: 127.1842
• NSC Number: 68637
• DSSTox Substance ID: DTXSID40290443
• Wikidata: Q82028104
• Mol file: 13105-73-2.mol

Synonyms:13105-73-2;NSC 68637;2-[ethyl(prop-2-yn-1-yl)amino]ethanol;NSC68637;NCIOpen2_000325;SCHEMBL5738098;DTXSID40290443;NSC-68637;2-(Ethyl-prop-2-ynyl-amino)-ethanol;AKOS009063241;N-ethyl-(2-hydroxyethyl)propargylamine

Chemical Property of 2-[Ethyl(prop-2-yn-1-yl)amino]ethanol

Chemical Property:

• Vapor Pressure: 0.0742mmHg at 25°C
• Boiling Point: 201.8°Cat760mmHg
• Flash Point: 82.1°C
• Density: 0.959g/cm³
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 127.099714038
• Heavy Atom Count: 9
• Complexity: 103

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CCO)CC#C

Technology Process of 2-[Ethyl(prop-2-yn-1-yl)amino]ethanol

There total 4 articles about 2-[Ethyl(prop-2-yn-1-yl)amino]ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl-(2-bromo-allyl)-amine (871-23-8) → 2-(Ethyl-2-propinylamino)-ethanol (13105-73-2)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. ethanol

2: NaNH₂, liq. NH₃, Et₂O, NH₄Cl

With diethyl ether; ammonia; ammonium chloride; sodium amide; In ethanol;

DOI:10.1021/jo01025a030

Reference yield:

N-Ethyl-N-<2-brom-allyl>-ethanolamin (89976-02-3) → 2-(Ethyl-2-propinylamino)-ethanol (13105-73-2)

Guidance literature:

With diethyl ether; ammonia; ammonium chloride; sodium amide;

DOI:10.1021/jo01025a030

Reference yield:

propargyl bromide (106-96-7) + 2-(Diethylamino)ethanol (100-37-8) → 2-(Ethyl-2-propinylamino)-ethanol (13105-73-2)

Guidance literature:

With potassium hydroxide; In 1,4-dioxane;

upstream raw materials:

N-Ethyl-N-<2-brom-allyl>-ethanolamin

propargyl bromide

2-(Diethylamino)ethanol

ethyl-(2-bromo-allyl)-amine

Downstream raw materials:

4-Ethyl-2-methylen-morpholin

3-Ethyl-2-vinyl-oxazolidin