2-diethoxyphosphoryl-N-methoxy-N-methylacetamide

Base Information

• Chemical Name: 2-diethoxyphosphoryl-N-methoxy-N-methylacetamide
• CAS No.: 124931-12-0
• Molecular Formula: C8H18 N O5 P
• Molecular Weight: 239.208
• Hs Code.: 29319000
• European Community (EC) Number: 626-937-0
• DSSTox Substance ID: DTXSID70378667
• Nikkaji Number: J860.320K
• Wikidata: Q82168183
• Mol file: 124931-12-0.mol

Synonyms:124931-12-0;Diethyl (N-methoxy-N-methylcarbamoylmethyl)phosphonate;2-diethoxyphosphoryl-N-methoxy-N-methylacetamide;Diethyl (2-(methoxy(methyl)amino)-2-oxoethyl)phosphonate;Diethyl(N-methoxy-N-methylcarbamoylmethyl)phosphonate;Diethyl N-methoxy-N-methylphosphonoacetamide;2-diethoxyphosphoryl-N-methoxy-N-methyl-acetamide;diethyl {[methoxy(methyl)carbamoyl]methyl}phosphonate;diethyl {2-[methoxy(methyl)amino]-2-oxoethyl}phosphonate;SBB057815;diethyl (n-methoxy-n-methylcarbamoyl-methyl)phosphonate;SCHEMBL224985;DTXSID70378667;WYLRYBDGIILFIR-UHFFFAOYSA-N;(N-Methoxy-N-methylcarbamoylmethyl)phosphonic Acid Diethyl Ester;ZEA93112;BBL102956;MFCD00134233;STL556765;AKOS015916081;AM803081;N-methoxy-N-methyl diethylphosphonoacetamide;CS-0037993;D3708;N-methoxy-N-methyl diethylphosphonoacetarnide;N-Methoxy-N-methyldiethoxyphosphinylacetamide;EN300-7415618;A890344;N-Methoxy-N-methyl-2-(diethyl phosphono)acetamide;J-005180;N-Methoxy-N-methyl-phosphonoacetamide diethyl ester;diethyl 2-(methoxy(methyl)amino)-2-oxoethylphosphonate;diethyl(N-methoxy-N-methyl-carbamoylmethyl)phosphonate;diethyl-(N-methoxy-N-methyl-carbamoylmethyl)-phosphonate;Diethyl (N-methoxy-N-methylcarbamoylmethyl)phosphonate, 96%

Chemical Property of 2-diethoxyphosphoryl-N-methoxy-N-methylacetamide

Chemical Property:

• Vapor Pressure: 0.00135mmHg at 25°C
• Refractive Index: n20/D 1.455(lit.)
• Boiling Point: 297.4°Cat760mmHg
• Flash Point: 133.7°C
• PSA: 74.88000
• Density: 1.148g/cm³
• LogP: 1.27230
• XLogP3: -0.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 239.09225967
• Heavy Atom Count: 15
• Complexity: 235

Purity/Quality:

98%,99%, ^*data from raw suppliers

Diethyl (N-methoxy-N-methylcarbamoylmethyl)phosphonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOP(=O)(CC(=O)N(C)OC)OCC
• Uses: Reactant for:Preparation of ring-expanded bryostatin analogs as antitumor agentsAsymmertic synthesis of pinnatoxins A and G via diastereoselective Ireland-Claisen rearrangement, ring closing metathesis, and cyclizationRh2(II)-catalyzed nitro-group migration reactionsStereoselective synthesis of cyclohexanones via phase transfer catalyzed double addition reactionsStereoselective synthesis of (+)-polyrhacitide A via aldol reaction, Horner-Wardsworth-Emmons reaction, Evans acetal intramolecular oxa-Michael reaction and diastereoselective syn reduction reaction as the key stepsPreparation of substituted furans via olefin cross-metathesis