2,8-Bis(4-chlorobenzylidene)cyclooctanone

Base Information

Chemical Name:2,8-Bis(4-chlorobenzylidene)cyclooctanone
CAS No.:52230-57-6
Molecular Formula:C22H20Cl2O
Molecular Weight:371.2996
Hs Code.:
Mol file:52230-57-6.mol

Synonyms:2,8-Bis(4-chlorobenzylidene)cyclooctanone;2,8-Bis((4-chlorophenyl)methylene)cyclooctanone;Cyclooctanone, 2,8-bis((4-chlorophenyl)methylene)-;52230-57-6

Suppliers and Price of 2,8-Bis(4-chlorobenzylidene)cyclooctanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2,8-Bis(4-chlorobenzylidene)cyclooctanone

Chemical Property:

Vapor Pressure:3.8E-12mmHg at 25°C
Boiling Point:550°C at 760 mmHg
Flash Point:228.6°C
Density:1.246g/cm³
XLogP3:7.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:370.0891206
Heavy Atom Count:25
Complexity:462

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(=CC2=CC=C(C=C2)Cl)C(=O)C(=CC3=CC=C(C=C3)Cl)CC1
Isomeric SMILES:C1CC/C(=C\C2=CC=C(C=C2)Cl)/C(=O)/C(=C/C3=CC=C(C=C3)Cl)/CC1

Technology Process of 2,8-Bis(4-chlorobenzylidene)cyclooctanone

There total 1 articles about 2,8-Bis(4-chlorobenzylidene)cyclooctanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 502-49-8
cycloactanone

: 104-88-1
4-chlorobenzaldehyde

: 52230-57-6
2,8-Bis-(4-chlor-benzyliden)-cyclooctanon

Guidance literature:: With piperidine; pyridine; for 4h; Heating;
DOI:10.1021/je00024a037

Reference yield: 80.0%

: 52230-57-6
2,8-Bis-(4-chlor-benzyliden)-cyclooctanon

: 17356-08-0
thiourea

: 77109-62-7
4-(4-Chloro-phenyl)-10-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-3,4,5,6,7,8,9,10-octahydro-1H-cyclooctapyrimidine-2-thione

Guidance literature:: With potassium hydroxide; In ethanol; for 3h; Heating;
DOI:10.1021/je00024a037

Reference yield:

: 52230-57-6
2,8-Bis-(4-chlor-benzyliden)-cyclooctanon

: 77109-72-9
4-(4-Chloro-phenyl)-10-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-2-[1-phenyl-meth-(Z)-ylidene]-5,6,7,8,9,10-hexahydro-4H-1-thia-3a,11-diaza-cycloocta[f]inden-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / KOH / ethanol / 3 h / Heating

2: 94 percent / NaOAc / acetic acid; acetic anhydride / 2.5 h / Heating

With potassium hydroxide; sodium acetate; In ethanol; acetic anhydride; acetic acid;
DOI:10.1021/je00024a037