2-(THIAZOL-4-YL)ETHYLAMINE

Base Information

• Chemical Name: 2-(THIAZOL-4-YL)ETHYLAMINE
• CAS No.: 7728-74-7
• Molecular Formula: C5H8N2S
• Molecular Weight: 128.1954
• Hs Code.: 2934100090
• Mol file: 7728-74-7.mol

Synonyms:2-(thiazole-4-yl)ethylamine;2-Thiazol-4-yl-ethylamine;2-(Thiazol-4-yl)ethanamine;2-(1,3-thiazol-4-yl)ethan-1-amine;4-(2-aminoethyl)-1,3-thiazole;2-(1,3-thiazol-4-yl)ethylamine;4-Thiazoleethanamine;2-Thiazol-4-yl-aethylamin;

Chemical Property of 2-(THIAZOL-4-YL)ETHYLAMINE

Chemical Property:

• Vapor Pressure: 0.0592mmHg at 25°C
• Melting Point: 206-207 °C
• Boiling Point: 232.4°Cat760mmHg
• PKA: 8.86±0.10(Predicted)
• Flash Point: 94.3°C
• PSA: 45.75000
• Density: 1.18g/cm³
• LogP: 1.37540
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

2-(1,3-thiazol-4-yl)ethan-1-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(THIAZOL-4-YL)ETHYLAMINE

There total 5 articles about 2-(THIAZOL-4-YL)ETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiazole-4-carbonitrile (1452-15-9) → 4-TEA (7728-74-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield:

N-(2-thiazol-4-yl-ethyl)-phthalimide (250258-56-1) → 4-TEA (7728-74-7)

Guidance literature:

With hydrazine hydrate;

DOI:10.1021/ja01166a052

Reference yield:

2-(thiazol-4-yl)acetonitrile (7709-59-3) → 4-TEA (7728-74-7)

Guidance literature:

With ethanol; ammonia; nickel; Hydrogenation;

DOI:10.1021/ja01166a052 DOI:10.1021/jo01166a021

upstream raw materials:

2-(thiazol-4-yl)acetonitrile

N-(2-thiazol-4-yl-ethyl)-phthalimide

-acetamid

thiazol-4-yl acetic acid ethyl ester

Downstream raw materials:

4-<2-Dimethylamino-ethyl>-thiazol

(R/S)-2-hydroxy-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)-N-(2-(thiazol-4-yl)ethyl)acetamide

4-[2-(4-Nitroanilino)ethyl]-1,3-thiazole

Refernces

• 1、 -. "CHK-, PDK- AND AKT-INHIBITORY PYRIMIDINES, THEIR PRODUCTION AND USE AS PHARMACEUTICAL AGENTS". Page 85. . Retrieved 2008/06/13.