10-(3,4-Dimethoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one

Base Information

Chemical Name:10-(3,4-Dimethoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one
CAS No.:137987-38-3
Molecular Formula:C19H19N3O3
Molecular Weight:337.3725
Hs Code.:
DSSTox Substance ID:DTXSID20929961
Nikkaji Number:J445.492H
ChEMBL ID:CHEMBL3478586

Synonyms:10-(3,4-Dimethoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one;137987-38-3;4-(3,4-dimethoxyphenyl)-2,4,5,10-tetrahydro-1H-pyrrolo[3,4-c][1,5]benzodiazepin-3-one;Pyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one, 3,4,9,10-tetrahydro-10-(3,4-dimethoxyphenyl)-, dihydrate;10-(3,4-dimethoxyphenyl)-3,4,9,10-tetrahydropyrrolo[3,4-b][1,5]benzodiazepin-1(2H)-one;Oprea1_244244;CBDivE_003910;CHEMBL3478586;DTXSID20929961;C19H19N3O3.2H2O;C19-H19-N3-O3.2H2-O;LS-139283;SR-01000199146;SR-01000199146-1;10-(3,4-Dimethoxyphenyl)-3,4,9,10-tetrahydropyrrolo[3,4-b][1,5]benzodiazepin-1-ol;3,4,9,10-Tetrahydro-10-(3,4-dimethoxyphenyl)pyrrolo[3,4-b][1,5]benzodiazepin-1(2H)-one

Suppliers and Price of 10-(3,4-Dimethoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 10-(3,4-Dimethoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one

Chemical Property:

Vapor Pressure:2.74E-14mmHg at 25°C
Boiling Point:598.6°Cat760mmHg
Flash Point:315.8°C
Density:1.34g/cm³
XLogP3:2.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:337.14264148
Heavy Atom Count:25
Complexity:550

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C2C3=C(CNC3=O)NC4=CC=CC=C4N2)OC

Technology Process of 10-(3,4-Dimethoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one

There total 2 articles about 10-(3,4-Dimethoxyphenyl)-3,4,9,10-tetrahydropyrrolo(3,4-b)(1,5)benzodiazepin-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 137987-35-0
4-(2-aminophenyl)aminopyrroline-2-one

: 137987-38-3
10-(3,4-Dimethoxy-phenyl)-3,4,9,10-tetrahydro-2H-benzo[b]pyrrolo[3,4-e][1,4]diazepin-1-one

Guidance literature:: With acetic acid; In ethanol;
DOI:10.1007/BF00767253

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 137987-38-3
10-(3,4-Dimethoxy-phenyl)-3,4,9,10-tetrahydro-2H-benzo[b]pyrrolo[3,4-e][1,4]diazepin-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / methanol / 1 h / Heating

2: 89 percent / AcOH / ethanol

With acetic acid; In methanol; ethanol;
DOI:10.1007/BF00767253