N-butyl-N-methyl-13,14-bis(4'-hydroxyphenyl)-12-thiatetradecanamide

Base Information

• Chemical Name: N-butyl-N-methyl-13,14-bis(4'-hydroxyphenyl)-12-thiatetradecanamide
• CAS No.: 155143-02-5
• Molecular Formula: C₃₀H₄₅NO₃S
• Molecular Weight: 499.758
• Mol file: 155143-02-5.mol

Synonyms:Undecanamide,11-[[1,2-bis(4-hydroxyphenyl)ethyl]thio]-N-butyl-N-methyl-, (?à)-

Chemical Property of N-butyl-N-methyl-13,14-bis(4'-hydroxyphenyl)-12-thiatetradecanamide

Chemical Property:

• Boiling Point: 645.6°Cat760mmHg
• Flash Point: 344.2°C
• PSA: 86.07000
• Density: 1.079g/cm³
• LogP: 7.88420

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-butyl-N-methyl-13,14-bis(4'-hydroxyphenyl)-12-thiatetradecanamide

There total 9 articles about N-butyl-N-methyl-13,14-bis(4'-hydroxyphenyl)-12-thiatetradecanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

N-butyl-N-methyl-11-mercaptoundecanamide (155142-85-1) + 1,2-bis<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanol (155142-80-6) → N-butyl-N-methyl-13,14-bis(4'-hydroxyphenyl)-12-thiatetradecanamide (155143-02-5) + 11-{1,2-Bis-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-ethylsulfanyl}-undecanoic acid butyl-methyl-amide

Guidance literature:

With zinc(II) iodide; In 1,2-dichloro-ethane; for 22h; Ambient temperature;

DOI:10.1021/jm00034a009

Reference yield:

N-n-butyl-N-methylamine (110-68-9) → N-butyl-N-methyl-13,14-bis(4'-hydroxyphenyl)-12-thiatetradecanamide (155143-02-5)

Guidance literature:

Multi-step reaction with 4 steps

1: CH₂Cl₂ / 3 h

2: ethanol

3: 10percent aq. NaOH

4: 28 percent / ZnI₂ / 1,2-dichloro-ethane / 22 h / Ambient temperature

With sodium hydroxide; zinc(II) iodide; In ethanol; dichloromethane; 1,2-dichloro-ethane;

DOI:10.1021/jm00034a009

Reference yield:

1,2-bis<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanone (89778-47-2) → N-butyl-N-methyl-13,14-bis(4'-hydroxyphenyl)-12-thiatetradecanamide (155143-02-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / NaBH₄ / methanol / 1 h / Ambient temperature

2: 28 percent / ZnI₂ / 1,2-dichloro-ethane / 22 h / Ambient temperature

With sodium tetrahydroborate; zinc(II) iodide; In methanol; 1,2-dichloro-ethane;

DOI:10.1021/jm00034a009

upstream raw materials:

N-butyl-N-methyl-11-mercaptoundecanamide

1,2-bis<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanol

N-n-butyl-N-methylamine

1,2-bis<4'-(tetrahydro-2''H-pyran-2''-yloxy)phenyl>ethanone