Bufetolol

Base Information

• Chemical Name: Bufetolol
• CAS No.: 53684-49-4
• Molecular Formula: C18H29 N O4
• Molecular Weight: 323.433
• Hs Code.: 2932190090
• UNII: WS1467RT9Z
• DSSTox Substance ID: DTXSID9057763
• Nikkaji Number: J10.891J
• Wikipedia: Bufetolol
• Wikidata: Q15634021
• NCI Thesaurus Code: C72612
• ChEMBL ID: CHEMBL347830
• Mol file: 53684-49-4.mol

Synonyms:1-tert-butylamino-3-(o-(tetrahydrofurfuryloxy)phenoxy)-2-propanol;Adobiol;bufetolol;bufetolol hydrochloride;Y 6124;Y-6124

Chemical Property of Bufetolol

Chemical Property:

• Vapor Pressure: 7E-10mmHg at 25°C
• Boiling Point: 476.4°Cat760mmHg
• PKA: 13.91±0.20(Predicted)
• Flash Point: 241.9°C
• PSA: 59.95000
• Density: 1.081g/cm³
• LogP: 2.76310
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Slightly),
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 9
• Exact Mass: 323.20965841
• Heavy Atom Count: 23
• Complexity: 332

Purity/Quality:

99% ^*data from raw suppliers

Bufetolol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)NCC(COC1=CC=CC=C1OCC2CCCO2)O
• Uses: Bufetolol is a β-adrenergic blocking agent and it inhibits the activation of adenyl cyclase.
• Therapeutic Function: Antiarrhythmic

Technology Process of Bufetolol

There total 1 articles about Bufetolol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Bufetolol (53684-49-4)

Guidance literature:

/BRN= 329110/, Hydrierung mit Raney-Nickel;

Refernces

• 1、 -. "ANTIHYPERTENSIVE THERAPY". . . Retrieved 2009/09/08.
• 2、 -. "Enteric coated mixture of 4-(2-hydroxy-3-isopropylamino-propoxy) indole and sodium lauryl sulphate". . . Retrieved 2008/06/13.