Cyclosporin lactam(3,4)

Base Information

• Chemical Name: Cyclosporin lactam(3,4)
• CAS No.: 115141-85-0
• Molecular Formula: C₆₄H₁₁₃N₁₁O₁₂
• Molecular Weight: 1228.67
• Mol file: 115141-85-0.mol

Synonyms:cyclosporin lactam(3,4)

Chemical Property of Cyclosporin lactam(3,4)

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 1307°Cat760mmHg
• Flash Point: 744.2°C
• PSA: 292.76000
• Density: 1.15g/cm³
• LogP: 4.47050
• XLogP3: 8.1
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 15
• Exact Mass: 1227.85701808
• Heavy Atom Count: 87
• Complexity: 2410

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1C(=O)N(C2CCCN(C2=O)C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C
• Isomeric SMILES: CCC1C(=O)N(C2CCCN(C2=O)C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C

Technology Process of Cyclosporin lactam(3,4)

There total 1 articles about Cyclosporin lactam(3,4) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C86H131N11O15 (115160-84-4) → 3,4>cyclosporine A (115141-85-0)

Guidance literature:

With dmap; sodium hydroxide; (PrPO₂)3; Yield given. Multistep reaction; 1.) ethanol, 0 deg C, 6.5 h, 2.) CH₂Cl₂, room temperature,28 h;

DOI:10.1021/jm00117a022

upstream raw materials:

C₈₆H₁₃₁N₁₁O₁₅

Refernces