N-(4-Aminophenyl)-1-pyrrolidinebutanamide

Base Information

Chemical Name:N-(4-Aminophenyl)-1-pyrrolidinebutanamide
CAS No.:875923-91-4
Molecular Formula:C14H21N3O
Molecular Weight:247.34
Hs Code.:
DSSTox Substance ID:DTXSID601270600

Synonyms:N-(4-Aminophenyl)-1-pyrrolidinebutanamide;SCHEMBL4749143;DTXSID601270600;AKOS000134748;875923-91-4

Suppliers and Price of N-(4-Aminophenyl)-1-pyrrolidinebutanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-Aminophenyl)-1-pyrrolidinebutanamide

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:247.168462302
Heavy Atom Count:18
Complexity:256

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(C1)CCCC(=O)NC2=CC=C(C=C2)N

Technology Process of N-(4-Aminophenyl)-1-pyrrolidinebutanamide

There total 3 articles about N-(4-Aminophenyl)-1-pyrrolidinebutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 875924-09-7
N-(4'-nitrophenyl)-4-(pyrrolidin-1-yl)butanamide

: 875923-91-4
N-(4-aminophenyl)-4-(pyrrolidin-1-yl)butanamide

Guidance literature:: With ammonium formate; palladium on activated charcoal; In ethanol; at 120 ℃; for 0.05h; microwave irradiation;
DOI:10.1021/jm050555a

Reference yield:

: 100-01-6,104810-17-5
4-nitro-aniline

: 875923-91-4
N-(4-aminophenyl)-4-(pyrrolidin-1-yl)butanamide

Guidance literature:: Multi-step reaction with 3 steps

1: 45 percent / 16 h / 20 °C

2: 54 percent / 24 h / 20 °C

3: 76 percent / ammonium formate / Pd/C / ethanol / 0.05 h / 120 °C / microwave irradiation

With ammonium formate; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm050555a

Reference yield:

: 82547-19-1
N-(4'-nitrophenyl)-4-chlorobutanamide

: 875923-91-4
N-(4-aminophenyl)-4-(pyrrolidin-1-yl)butanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 54 percent / 24 h / 20 °C

2: 76 percent / ammonium formate / Pd/C / ethanol / 0.05 h / 120 °C / microwave irradiation

With ammonium formate; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm050555a