2-Methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo(1,5-a)pyridine

Base Information

Chemical Name:2-Methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo(1,5-a)pyridine
CAS No.:94457-09-7
Molecular Formula:C₁₄H₁₅N₃O
Molecular Weight:241.293
Hs Code.:
DSSTox Substance ID:DTXSID60241497
Nikkaji Number:J391.070I
Wikidata:Q83125011
Mol file:94457-09-7.mol

Synonyms:2-methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo(1,5-a)pyridine;KC 764;KC-764

Suppliers and Price of 2-Methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo(1,5-a)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-METHYL-3-(1,4,5,6-TETRAHYDRONICOTINOYL)PYRAZOLO(1,5-A)PYRIDINE 95.00%
5MG
$ 500.91

Total 5 raw suppliers

Chemical Property of 2-Methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo(1,5-a)pyridine

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：46.40000
Density:1.27g/cm³
LogP:2.42150
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:241.121512110
Heavy Atom Count:18
Complexity:366

Purity/Quality:

99% ^*data from raw suppliers

2-METHYL-3-(1,4,5,6-TETRAHYDRONICOTINOYL)PYRAZOLO(1,5-A)PYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=NN2C=CC=CC2=C1C(=O)C3=CNCCC3

Technology Process of 2-Methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo(1,5-a)pyridine

There total 3 articles about 2-Methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo(1,5-a)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 94457-08-6
2-methyl-3-nicotinoylpyrazolo<1,5-α>pyridine

: 94457-09-7
2-methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo<1,5-α>pyridine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 55 - 58 ℃; for 3h; under 7600 Torr;
DOI:10.1248/cpb.34.2828

Reference yield:

: 20260-53-1
pyridine-3-carbonyl chloride hydrochloride

: 94457-09-7
2-methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo<1,5-α>pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / dioxane / 2 h / Heating

2: 63 percent / H₂ / palladium-carbon / ethanol / 3 h / 55 - 58 °C / 7600 Torr

With hydrogen; palladium on activated charcoal; In 1,4-dioxane; ethanol;
DOI:10.1248/cpb.34.2828

Reference yield:

: 34760-58-2
2-methylpyrazolo<1,5-α>pyridine

: 94457-09-7
2-methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo<1,5-α>pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / dioxane / 2 h / Heating

2: 63 percent / H₂ / palladium-carbon / ethanol / 3 h / 55 - 58 °C / 7600 Torr

With hydrogen; palladium on activated charcoal; In 1,4-dioxane; ethanol;
DOI:10.1248/cpb.34.2828