20,29,30-Trinor-3beta-hydroxy-28,19beta-lupanolide

Base Information

Chemical Name:20,29,30-Trinor-3beta-hydroxy-28,19beta-lupanolide
CAS No.:122689-50-3
Molecular Formula:C₂₇H₄₂O₃
Molecular Weight:414.629
Hs Code.:
Wikidata:Q110187599

Synonyms:Diospyrolide;20,29,30-Trinor-3beta-hydroxy-28,19beta-lupanolide;20,29,30-Trinorlupan-28-oic acid, 3,19-dihydroxy-, gamma-lactone, (3beta,19beta)-

Suppliers and Price of 20,29,30-Trinor-3beta-hydroxy-28,19beta-lupanolide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 20,29,30-Trinor-3beta-hydroxy-28,19beta-lupanolide

Chemical Property:

Vapor Pressure:1.11E-13mmHg at 25°C
Boiling Point:535.1°Cat760mmHg
Flash Point:205.8°C
Density:1.13g/cm³
XLogP3:6.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:414.31339520
Heavy Atom Count:30
Complexity:789

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C2CCC3(C(C2(CCC1O)C)CCC4C3(CCC56C4C(CC5)OC6=O)C)C)C
Isomeric SMILES:C[C@@]12CCC34CC[C@H]([C@@H]3[C@H]1CC[C@H]5[C@]2(CC[C@@H]6[C@@]5(CC[C@@H](C6(C)C)O)C)C)OC4=O

Technology Process of 20,29,30-Trinor-3beta-hydroxy-28,19beta-lupanolide

There total 5 articles about 20,29,30-Trinor-3beta-hydroxy-28,19beta-lupanolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 756782-76-0
(3aS,5aR,5bR,7aR,9S,11aR,11bR,13aS)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-2,3,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-cyclopenta[a]chrysene-3a-carboxylic acid

: 122689-50-3
diospyrolide

Guidance literature:: With hydrogenchloride; In chloroform; at 0 ℃; for 50h;
DOI:10.1016/S0040-4039(00)82198-X

Reference yield:

: 4356-30-3,25488-52-2
Acetylmethylbetulinate

: 122689-50-3
diospyrolide

Guidance literature:: Multi-step reaction with 5 steps

1: 70 percent / SeO₂ / acetic acid / 3 h / Heating

2: 60 percent / CrO₃ / aq. acetic acid / 15 h / 30 °C

3: Cu(OAc)2, pyridine / benzene / 4 h / Heating

4: 70 percent / t-BuOK, DMSO / 3 h / 100 °C

5: 40 percent / HCl / CHCl₃ / 50 h / 0 °C

With pyridine; chromium(VI) oxide; hydrogenchloride; selenium(IV) oxide; copper diacetate; potassium tert-butylate; dimethyl sulfoxide; In chloroform; acetic acid; benzene;
DOI:10.1016/S0040-4039(00)82198-X

Reference yield:

: 122689-49-0
(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bS)-9-Acetoxy-5a,5b,8,8,11a-pentamethyl-icosahydro-cyclopenta[a]chrysene-1,3a-dicarboxylic acid 3a-methyl ester

: 122689-50-3
diospyrolide

Guidance literature:: Multi-step reaction with 3 steps

1: Cu(OAc)2, pyridine / benzene / 4 h / Heating

2: 70 percent / t-BuOK, DMSO / 3 h / 100 °C

3: 40 percent / HCl / CHCl₃ / 50 h / 0 °C

With pyridine; hydrogenchloride; copper diacetate; potassium tert-butylate; dimethyl sulfoxide; In chloroform; benzene;
DOI:10.1016/S0040-4039(00)82198-X