3,3-Difluoroandrostane-17-ol acetate

Base Information

Chemical Name:3,3-Difluoroandrostane-17-ol acetate
CAS No.:1827-75-4
Molecular Formula:C21H32 F2 O2
Molecular Weight:354.481
Hs Code.:
NSC Number:53900
UNII:PO853GYS65
DSSTox Substance ID:DTXSID001226174
Nikkaji Number:J507.807E
Wikidata:Q27115988
Mol file:1827-75-4.mol

Synonyms:3,3-diFAO-Ac;3,3-difluoro-5alpha-androstane-17beta-ol acetate;3,3-difluoroandrostane-17-ol acetate

Suppliers and Price of 3,3-Difluoroandrostane-17-ol acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 20 raw suppliers

Chemical Property of 3,3-Difluoroandrostane-17-ol acetate

Chemical Property:

Vapor Pressure:2.08E-06mmHg at 25°C
Boiling Point:393.7°C at 760 mmHg
Flash Point:185.3°C
PSA：26.30000
Density:1.12g/cm³
LogP:5.59610
XLogP3:6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:354.23703658
Heavy Atom Count:25
Complexity:562

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1CCC2C1(CCC3C2CCC4C3(CCC(C4)(F)F)C)C
Isomeric SMILES:CC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CCC(C4)(F)F)C)C

Technology Process of 3,3-Difluoroandrostane-17-ol acetate

There total 6 articles about 3,3-Difluoroandrostane-17-ol acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1164-91-6
stanolone acetate

: 1827-75-4
3,3-difluoro-5α-androstane-17β-ol acetate

Guidance literature:: With (diethylamido)sulfur trifluoride; at 80 ℃; for 3.5h;
DOI:10.1021/jm00089a024

Reference yield: 70.0%

: 19640-01-8
17β-Acetoxy-5α-androstan-3-one hydrazone

: 1827-75-4
3,3-difluoro-5α-androstane-17β-ol acetate

Guidance literature:: With iodine monofluoride; In chloroform; for 0.5h; Ambient temperature;
DOI:10.1021/jo00015a024

Reference yield:

: 521-18-6
Stanolone

: 1827-75-4
3,3-difluoro-5α-androstane-17β-ol acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 98.3 percent / pyridine / CH₂Cl₂ / 2 h / Ambient temperature

2: 91 percent / (diethylamido)sulfur trifluoride / 3.5 h / 80 °C

With pyridine; (diethylamido)sulfur trifluoride; In dichloromethane;
DOI:10.1021/jm00089a024