Luvangetin

Base Information

• Chemical Name: Luvangetin
• CAS No.: 483-92-1
• Molecular Formula: C15H14O4
• Molecular Weight: 258.2693
• NSC Number: 383464
• DSSTox Substance ID: DTXSID60197485
• Nikkaji Number: J12.540G
• Wikidata: Q27107252
• Metabolomics Workbench ID: 68465
• ChEMBL ID: CHEMBL254379
• Mol file: 483-92-1.mol

Synonyms:Luvangetin;483-92-1;10-methoxy-2,2-dimethylpyrano[3,2-g]chromen-8-one;CHEBI:6586;C09273;10-METHOXY-8,8-DIMETHYL-2H,8H-PYRANO[3,2-G]CHROMEN-2-ONE;2H,8H-Benzo(1,2-b:5,4-b')dipyran-2-one, 10-methoxy-8,8-dimethyl-;10-Methoxy-8,8-dimethyl-2H,8H-benzo[1,2-b;10-Methoxy-8,8-dimethyl-2H,8H-benzo(1,2-b:5,4-b')dipyran-2-one;10-Methoxy-8,8-dimethyl-2H,8H-benzo[1,2-b:5,4-b']dipyran-2-one;AC1L7YNQ;starbld0003698;CHEMBL254379;SCHEMBL14511557;DTXSID60197485;NSC383464;AKOS040762006;NSC-383464;E88907;10-methoxy-2,2-dimethyl-pyrano[3,2-g]chromen-8-one;Q27107252

Chemical Property of Luvangetin

Chemical Property:

• Vapor Pressure: 1.17E-07mmHg at 25°C
• Boiling Point: 431.8°Cat760mmHg
• Flash Point: 193.9°C
• PSA: 48.67000
• Density: 1.225g/cm³
• LogP: 2.98580
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 258.08920892
• Heavy Atom Count: 19
• Complexity: 437

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(C=CC2=C(O1)C(=C3C(=C2)C=CC(=O)O3)OC)C

Technology Process of Luvangetin

There total 13 articles about Luvangetin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

10-hydroxy-8,8-dimethyl-2H,8H-pyrano[3,2-g]chromen-2-one (64652-10-4) + dimethyl sulfate (77-78-1) → luvangetin (483-92-1)

Guidance literature:

With potassium carbonate; In acetone;

Reference yield: 65.0%

dihydroluvangetin (7777-11-9) → luvangetin (483-92-1)

Guidance literature:

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); potassium carbonate; In benzene; for 2.5h; Heating;

DOI:10.1039/b109597h

Reference yield:

demethyldihydroluvangetin (40046-38-6) → luvangetin (483-92-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / K₂CO₃ / dimethylformamide / 1 h / 20 °C

2: 65 percent / NBS; AIBN; K₂CO₃ / benzene / 2.5 h / Heating

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); potassium carbonate; In N,N-dimethyl-formamide; benzene;

DOI:10.1039/b109597h

upstream raw materials:

hydrangetin

2-methyl-but-3-yn-2-ol

10-hydroxy-8,8-dimethyl-2H,8H-pyrano[3,2-g]chromen-2-one

dimethyl sulfate