Technology Process of Silane,
(1,1-dimethylethyl)[(S)-1-(2-iodoethyl)-3-phenylpropoxy]dimethyl-
There total 9 articles about Silane,
(1,1-dimethylethyl)[(S)-1-(2-iodoethyl)-3-phenylpropoxy]dimethyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1H-imidazole; iodine; triphenylphosphine;
In
dichloromethane;
at 20 ℃;
for 1h;
Schlenk technique;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: bis(1,5-cyclooctadiene)diiridium(I) dichloride; (R)-(-)-Cl-MeOBIPHEP; caesium carbonate; 3-nitrobenzoic acid / tetrahydrofuran / 20 h / 100 °C / Sealed tube
2.1: 1H-imidazole; dmap / dichloromethane / 20 h / 20 °C / Inert atmosphere
3.1: ozone / methanol / 0.25 h / -78 °C
3.2: 2 h / -78 - 20 °C
4.1: 1H-imidazole; triphenylphosphine; iodine / dichloromethane / 1 h / 20 °C / Inert atmosphere; Schlenk technique
With
1H-imidazole; dmap; bis(1,5-cyclooctadiene)diiridium(I) dichloride; (R)-(-)-Cl-MeOBIPHEP; iodine; caesium carbonate; ozone; triphenylphosphine; 3-nitrobenzoic acid;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ol503520f
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1H-imidazole; dmap / dichloromethane / 20 h / 20 °C / Inert atmosphere
2.1: ozone / methanol / 0.25 h / -78 °C
2.2: 2 h / -78 - 20 °C
3.1: 1H-imidazole; triphenylphosphine; iodine / dichloromethane / 1 h / 20 °C / Inert atmosphere; Schlenk technique
With
1H-imidazole; dmap; iodine; ozone; triphenylphosphine;
In
methanol; dichloromethane;
DOI:10.1021/ol503520f
