Technology Process of Benzene, 1,3-dimethoxy-5-[(1E)-2-(3-nitrophenyl)ethenyl]-
There total 5 articles about Benzene, 1,3-dimethoxy-5-[(1E)-2-(3-nitrophenyl)ethenyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
diethyl 3,5-dimethoxybenzylphosphonate;
With
sodium methylate;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 1h;
3-nitro-benzaldehyde;
In
N,N-dimethyl-formamide;
at 20 - 100 ℃;
for 11h;
Inert atmosphere;
DOI:10.14233/ajchem.2014.16226
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate; tetrabutylammomium bromide / N,N-dimethyl-formamide / 58 h / 140 °C
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 11 h / 0 - 20 °C
3.1: phosphorus tribromide / dichloromethane / 2 h / 0 °C
4.1: 7 h / 135 °C
5.1: sodium methylate / N,N-dimethyl-formamide / 1 h / 0 °C
5.2: 11 h / 20 - 100 °C / Inert atmosphere
With
lithium aluminium tetrahydride; tetrabutylammomium bromide; sodium methylate; phosphorus tribromide; potassium carbonate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
4.1: |Arbuzov Reaction / 5.2: |Wittig-Horner Reaction;
DOI:10.14233/ajchem.2014.16226
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 11 h / 0 - 20 °C
2.1: phosphorus tribromide / dichloromethane / 2 h / 0 °C
3.1: 7 h / 135 °C
4.1: sodium methylate / N,N-dimethyl-formamide / 1 h / 0 °C
4.2: 11 h / 20 - 100 °C / Inert atmosphere
With
lithium aluminium tetrahydride; sodium methylate; phosphorus tribromide;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
3.1: |Arbuzov Reaction / 4.2: |Wittig-Horner Reaction;
DOI:10.14233/ajchem.2014.16226
