1-(2,2-Difluoroethyl)-3-(trifluoromethyl)benzene

Base Information

Chemical Name:1-(2,2-Difluoroethyl)-3-(trifluoromethyl)benzene
CAS No.:50562-17-9
Molecular Formula:C9H7F5
Molecular Weight:210.1439
Hs Code.:
NSC Number:142242
DSSTox Substance ID:DTXSID10301297
Wikidata:Q82045039
Mol file:50562-17-9.mol

Synonyms:50562-17-9;1-(2,2-difluoroethyl)-3-(trifluoromethyl)benzene;NSC142242;DTXSID10301297;NSC-142242

Suppliers and Price of 1-(2,2-Difluoroethyl)-3-(trifluoromethyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-(2,2-Difluoroethyl)-3-(trifluoromethyl)benzene

Chemical Property:

Vapor Pressure:3.31mmHg at 25°C
Boiling Point:159°Cat760mmHg
Flash Point:50.2°C
Density:1.258g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:210.04679103
Heavy Atom Count:14
Complexity:175

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C(F)(F)F)CC(F)F

Technology Process of 1-(2,2-Difluoroethyl)-3-(trifluoromethyl)benzene

There total 4 articles about 1-(2,2-Difluoroethyl)-3-(trifluoromethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [bis(difluoromethyl)zinc(dmpu)₂]

: 4-(4-fluorophenyl)-1-(3-(trifluoromethyl)benzyl)-2,6-bis(4-(trifluoromethyl)phenyl)pyridin-1-ium tetrafluoroborate

: 50562-17-9
1,1-Difluor-2-(m-trifluormethylphenyl)ethan

Guidance literature:: With 2,2':6,2''-terpyridine; tetrakis(acetonitrile)copper(I)tetrafluoroborate; In dimethyl sulfoxide; at 60 ℃; for 12h; Inert atmosphere; Glovebox;
DOI:10.1002/anie.202006048

Reference yield:

: 50562-16-8
Toluene-4-sulfonic acid 2,2-difluoro-1-(3-trifluoromethyl-phenyl)-ethyl ester

: 50562-17-9
1,1-Difluor-2-(m-trifluormethylphenyl)ethan

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jo00921a004

Reference yield:

: 50562-15-7
1-(m-Trifluormethylphenyl)-2,2-difluorethanol

: 50562-17-9
1,1-Difluor-2-(m-trifluormethylphenyl)ethan

Guidance literature:: Multi-step reaction with 2 steps

2: H₂ / Pd-C / ethanol

With hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jo00921a004