Methyl 4-hydroxy-1-methylcyclohexane-1-carboxylate

Base Information

Chemical Name:Methyl 4-hydroxy-1-methylcyclohexane-1-carboxylate
CAS No.:87787-05-1
Molecular Formula:C9H16O3
Molecular Weight:172.22200
Hs Code.:
DSSTox Substance ID:DTXSID801222188

Synonyms:87787-05-1;87787-02-8;(1R,4r)-methyl 4-hydroxy-1-methylcyclohexanecarboxylate;37480-42-5;methyl 4-hydroxy-1-methylcyclohexane-1-carboxylate;methyl 4-hydroxy-1-methyl-cyclohexanecarboxylate;Cyclohexanecarboxylic acid, 4-hydroxy-1-methyl-, methyl ester, cis-;(1S,4s)-methyl 4-hydroxy-1-methylcyclohexanecarboxylate;cyclohexanecarboxylic acid, 4-hydroxy-1-methyl-, methyl ester, trans-;Methyl cis-4-hydroxy-1-methyl-cyclohexanecarboxylate;Methyl (1S,4S)-4-hydroxy-1-methylcyclohexane-1-carboxylate;methyl cis-4-hydroxy-1-methylcyclohexane-1-carboxylate;SCHEMBL3883900;SCHEMBL9041790;methyl trans-4-hydroxy-1-methylcyclohexane-1-carboxylate;SCHEMBL15115826;4-Hydroxy-1-methyl-cyclohexanecarboxylic acid methyl ester;BAGVQRARNBDKOA-UHFFFAOYSA-N;DTXSID801222188;MFCD28502412;SB18533;SB18534;PS-15979;PS-16997;PS-16998;CS-0056838;CS-0056839;CS-0451801;F89046;methyl 4-hydroxy-1-methylcyclohexanecarboxylate;P15006;P15007;P15734;P15735;Methyl cis-4-hydroxy-1-methylcyclohexanecarboxylate;methyl trans-4-hydroxy-1-methyl-cyclohexanecarboxylate;4-hydroxy-1-methylcyclohexanecarboxylic acid methyl ester;METHYL TRANS-4-HYDROXY-1-METHYLCYCLOHEXANECARBOXYLATE

Suppliers and Price of Methyl 4-hydroxy-1-methylcyclohexane-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(1S,4s)-methyl4-hydroxy-1-methylcyclohexanecarboxylate 97%
1g
$ 1382.00

Total 6 raw suppliers

Chemical Property of Methyl 4-hydroxy-1-methylcyclohexane-1-carboxylate

Chemical Property:

PSA：46.53000
LogP:1.10060
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:172.109944368
Heavy Atom Count:12
Complexity:169

Purity/Quality:

97% ^*data from raw suppliers

(1S,4s)-methyl4-hydroxy-1-methylcyclohexanecarboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(CCC(CC1)O)C(=O)OC

Technology Process of Methyl 4-hydroxy-1-methylcyclohexane-1-carboxylate

There total 3 articles about Methyl 4-hydroxy-1-methylcyclohexane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1523-89-3
methyl 1-methyl-4-oxo-2-cyclohexene-1-carboxylate

: 87787-05-1
methyl c-4-hydroxy-1-methyl-r-1-cyclohexanecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 95.4 percent / H₂ / Pd-C (50percent wet) / ethyl acetate / 760 Torr

2: 1.) H₂; 2.) 2N KOH / 1.) PtO₂ / 1.) AcOH, RT, 1 atm; 2.) MeOH, reflux, 1 h

3: diethyl ether

With potassium hydroxide; hydrogen; platinum(IV) oxide; palladium on activated charcoal; In diethyl ether; ethyl acetate;
DOI:10.1248/cpb.32.2267

Reference yield:

: 37480-41-4
methyl 1-methyl-4-oxo-1-cyclohexanecarboxylate

: 87787-05-1
methyl c-4-hydroxy-1-methyl-r-1-cyclohexanecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) H₂; 2.) 2N KOH / 1.) PtO₂ / 1.) AcOH, RT, 1 atm; 2.) MeOH, reflux, 1 h

2: diethyl ether

With potassium hydroxide; hydrogen; platinum(IV) oxide; In diethyl ether;
DOI:10.1248/cpb.32.2267