Corticrocin

Base Information

Chemical Name:Corticrocin
CAS No.:505-53-3
Molecular Formula:C₁₄H₁₄O₄
Molecular Weight:246.263
Hs Code.:2917190090
UNII:VBK1TSG361
Metabolomics Workbench ID:74903
Nikkaji Number:J133.857I
Wikidata:Q27896461
Mol file:505-53-3.mol

Synonyms:Corticrocin;505-53-3;VBK1TSG361;UNII-VBK1TSG361;2,4,6,8,10,12-Tetradecahexaenedioic acid, (all-E)-;(2E,4E,6E,8E,10E,12E)-2,4,6,8,10,12-Tetradecahexaenedioic acid;(2E,4E,6E,8E,10E,12E)-tetradeca-2,4,6,8,10,12-hexaenedioic acid;2,4,6,8,10,12-Tetradecahexaenedioic acid, (2E,4E,6E,8E,10E,12E)-;2E,4E,6E,8E,10E,12E-tetradecahexaenedioic acid;CHEBI:174273;LMFA01031041;Q27896461

Suppliers and Price of Corticrocin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Corticrocin

Chemical Property:

PSA：74.60000
LogP:2.49280
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:246.08920892
Heavy Atom Count:18
Complexity:393

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(=CC=CC=CC(=O)O)C=CC=CC=CC(=O)O
Isomeric SMILES:C(=C/C=C/C=C/C(=O)O)\C=C\C=C\C=C\C(=O)O

Technology Process of Corticrocin

There total 15 articles about Corticrocin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 5941-45-7
diethyl corticrocin

: 505-53-3
corticrocin

Guidance literature:: With potassium hydroxide; In methanol; water; for 12h; Ambient temperature;
DOI:10.1021/jo00312a031

Reference yield:

: 36707-31-0
1,2-bis(furan-2-yl)ethane

: 505-53-3
corticrocin

Guidance literature:: Multi-step reaction with 4 steps

1: 2) boron trifluoride etherate / 1) dirhodium tetraacetate / 1) CH₂Cl₂, 25 h, 2) RT, 1 h

2: NaBH₄, CeCl₃*7H₂O / CH₂Cl₂; ethanol / 0.17 h

3: 70 percent / para-methylated variant of Martin reagent / CH₂Cl₂ / 1) -100 deg C, 6 h, 2) warm to RT, 3) RT, 12 h

4: 86 percent / KOH / methanol; H₂O / 12 h / Ambient temperature

With potassium hydroxide; sodium tetrahydroborate; cerium(III) chloride; para-methylated variant of Martin reagent; boron trifluoride diethyl etherate; dirhodium tetraacetate; In methanol; ethanol; dichloromethane; water;
DOI:10.1021/jo00312a031

Reference yield:

: 51490-07-4
1,2-di(furan-2-yl)ethanone

: 505-53-3
corticrocin

Guidance literature:: Multi-step reaction with 5 steps

1: 62 percent / hydrazine hydrate, KOH / bis-(2-hydroxy-ethyl) ether / 1) 120 deg C, 0.5 h, 2) 185 deg C, 1.5. h

2: 2) boron trifluoride etherate / 1) dirhodium tetraacetate / 1) CH₂Cl₂, 25 h, 2) RT, 1 h

3: NaBH₄, CeCl₃*7H₂O / CH₂Cl₂; ethanol / 0.17 h

4: 70 percent / para-methylated variant of Martin reagent / CH₂Cl₂ / 1) -100 deg C, 6 h, 2) warm to RT, 3) RT, 12 h

5: 86 percent / KOH / methanol; H₂O / 12 h / Ambient temperature

With potassium hydroxide; sodium tetrahydroborate; cerium(III) chloride; para-methylated variant of Martin reagent; boron trifluoride diethyl etherate; hydrazine hydrate; dirhodium tetraacetate; In methanol; ethanol; dichloromethane; water; diethylene glycol;
DOI:10.1021/jo00312a031