Laciniatin

Base Information

Chemical Name:Laciniatin
CAS No.:74161-28-7
Molecular Formula:C₁₇H₁₄O₈
Molecular Weight:346.293
Hs Code.:
UNII:073088SZAR
DSSTox Substance ID:DTXSID30225123
Metabolomics Workbench ID:26079
Nikkaji Number:J819.307J
Wikidata:Q27236249

Synonyms:Laciniatin;74161-28-7;UNII-073088SZAR;073088SZAR;DTXSID30225123;3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-6-methoxy-4H-chromen-4-one;4H-1-BENZOPYRAN-4-ONE, 3,5,7-TRIHYDROXY-2-(3-HYDROXY-4-METHOXYPHENYL)-6-METHOXY-;DTXCID30147614;LMPK12112996;AKOS040752376;Q27236249;3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-6-methoxychromen-4-one

Suppliers and Price of Laciniatin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Laciniatin

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:346.06886740
Heavy Atom Count:25
Complexity:547

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(O2)C=C(C(=C3O)OC)O)O)O

Technology Process of Laciniatin

There total 12 articles about Laciniatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 188927-60-8
7-Benzyloxy-2-(3-benzyloxy-4-methoxy-phenyl)-3,5-dihydroxy-6-methoxy-chromen-4-one

: 74161-28-7
3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxy-phenyl)-6-methoxy-chromen-4-one

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; ethyl acetate; Ambient temperature;
DOI:10.1248/cpb.45.446

Reference yield:

: 3162-52-5
1-(4-benzyloxy-2-hydroxy-3,6-dimethoxy-phenyl)-ethanone

: 74161-28-7
3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxy-phenyl)-6-methoxy-chromen-4-one

Guidance literature:: Multi-step reaction with 10 steps

1: 83 percent / K₂CO₃, KI / acetone; dimethylformamide / Heating

2: 75 percent / AlBr₃, NaI / acetonitrile / 0.25 h / 0 °C

3: pyridine / 2 h / 70 - 80 °C

4: KOH / pyridine / 80 °C

5: 92 percent / conc. H₂SO₄, acetic acid / 1 h / 50 °C

6: 74 percent / dimethyldioxirane / acetone / 0 °C

7: 85 percent / K₂CO₃ / acetone / Heating

8: 83 percent / AlCl₃ / acetonitrile / 0.5 h / Ambient temperature

9: 88 percent / K₂CO₃ / methanol / 1.5 h / Heating

10: 89 percent / H₂ / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature

With pyridine; potassium hydroxide; aluminium trichloride; aluminum tri-bromide; sulfuric acid; hydrogen; 3,3-dimethyldioxirane; potassium carbonate; acetic acid; potassium iodide; sodium iodide; palladium on activated charcoal; In pyridine; methanol; ethyl acetate; N,N-dimethyl-formamide; acetone; acetonitrile;
DOI:10.1248/cpb.45.446

Reference yield:

: 3162-51-4
1-(2,4-Bis-benzyloxy-3,6-dimethoxy-phenyl)-ethanone

: 74161-28-7
3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxy-phenyl)-6-methoxy-chromen-4-one

Guidance literature:: Multi-step reaction with 11 steps

1: 100 percent / conc. HCl, acetic acid / 1 h / Ambient temperature

2: 83 percent / K₂CO₃, KI / acetone; dimethylformamide / Heating

3: 75 percent / AlBr₃, NaI / acetonitrile / 0.25 h / 0 °C

4: pyridine / 2 h / 70 - 80 °C

5: KOH / pyridine / 80 °C

6: 92 percent / conc. H₂SO₄, acetic acid / 1 h / 50 °C

7: 74 percent / dimethyldioxirane / acetone / 0 °C

8: 85 percent / K₂CO₃ / acetone / Heating

9: 83 percent / AlCl₃ / acetonitrile / 0.5 h / Ambient temperature

10: 88 percent / K₂CO₃ / methanol / 1.5 h / Heating

11: 89 percent / H₂ / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature

With pyridine; hydrogenchloride; potassium hydroxide; aluminium trichloride; aluminum tri-bromide; sulfuric acid; hydrogen; 3,3-dimethyldioxirane; potassium carbonate; acetic acid; potassium iodide; sodium iodide; palladium on activated charcoal; In pyridine; methanol; ethyl acetate; N,N-dimethyl-formamide; acetone; acetonitrile;
DOI:10.1248/cpb.45.446