3-Cyclohexene-1,1-dicarboxylic acid, 4-methyl-6-(4-nitrophenyl)-, mono[2-[3-ethoxy-2-(ethoxycarbonyl)-3-oxo-1-propenyl]hydrazide]

Base Information

• Chemical Name: 3-Cyclohexene-1,1-dicarboxylic acid, 4-methyl-6-(4-nitrophenyl)-, mono[2-[3-ethoxy-2-(ethoxycarbonyl)-3-oxo-1-propenyl]hydrazide]
• CAS No.: 878004-07-0
• Molecular Formula: C23H27N3O9
• Molecular Weight: 489.482
• Mol file: 878004-07-0.mol

Synonyms:

Chemical Property of 3-Cyclohexene-1,1-dicarboxylic acid, 4-methyl-6-(4-nitrophenyl)-, mono[2-[3-ethoxy-2-(ethoxycarbonyl)-3-oxo-1-propenyl]hydrazide]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Cyclohexene-1,1-dicarboxylic acid, 4-methyl-6-(4-nitrophenyl)-, mono[2-[3-ethoxy-2-(ethoxycarbonyl)-3-oxo-1-propenyl]hydrazide]

There total 1 articles about 3-Cyclohexene-1,1-dicarboxylic acid, 4-methyl-6-(4-nitrophenyl)-, mono[2-[3-ethoxy-2-(ethoxycarbonyl)-3-oxo-1-propenyl]hydrazide] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.6%

diethyl 2-ethoxymethylenemalonate (87-13-8) + 1-hydrazinocarbonyl-4-methyl-6-(4-nitro-phenyl)-cyclohex-3-enecarboxylic acid → 2-{N'-[1-carboxy-4-methyl-6-(4-nitro-phenyl)-cyclohex-3-enecarbonyl]-hydrazinomethylene}-malonic acid diethyl ester (878004-07-0)

Guidance literature:

In ethanol; for 1h; Heating;

DOI:10.1007/s10593-005-0125-4

Reference yield: 85.7%

2-{N'-[1-carboxy-4-methyl-6-(4-nitro-phenyl)-cyclohex-3-enecarbonyl]-hydrazinomethylene}-malonic acid diethyl ester (878004-07-0) + acetic anhydride (108-24-7) → 2-[4-acetoxy-8-methyl-10-(4-nitro-phenyl)-1-oxo-2,3-diaza-spiro[4.5]deca-3,7-dien-2-ylmethylene]-malonic acid diethyl ester

Guidance literature:

for 1h; Heating;

DOI:10.1007/s10593-005-0125-4

Reference yield: 80.1%

2-{N'-[1-carboxy-4-methyl-6-(4-nitro-phenyl)-cyclohex-3-enecarbonyl]-hydrazinomethylene}-malonic acid diethyl ester (878004-07-0) → 5-hydroxy-1-[4-methyl-6-(4-nitro-phenyl)-cyclohex-3-enecarbonyl]-1H-pyrazole-4-carboxylic acid ethyl ester

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 2h; Heating;

DOI:10.1007/s10593-005-0237-x

upstream raw materials:

diethyl 2-ethoxymethylenemalonate