N-[4-(hexyloxy)phenyl]acetamide

Base Information

• Chemical Name: N-[4-(hexyloxy)phenyl]acetamide
• CAS No.: 41240-77-1
• Molecular Formula: C14H21 N O2
• Molecular Weight: 235.326
• Hs Code.: 2924299090
• European Community (EC) Number: 255-276-7
• UNII: CH3EX55EZU
• DSSTox Substance ID: DTXSID4068290
• Nikkaji Number: J320.033G
• Wikidata: Q81995003
• Mol file: 41240-77-1.mol

Synonyms:N-[4-(hexyloxy)phenyl]acetamide;41240-77-1;Acetamide, N-[4-(hexyloxy)phenyl]-;N-(4-(Hexyloxy)phenyl)acetamide;EINECS 255-276-7;Acetamide, N-(4-(hexyloxy)phenyl)-;CH3EX55EZU;SCHEMBL8733277;DTXSID4068290;STL065491;AKOS000499508;N-(4-HEXYLOXY-PHENYL)-ACETAMIDE;NCGC00326227-01;AB01320754-02

Chemical Property of N-[4-(hexyloxy)phenyl]acetamide

Chemical Property:

• Vapor Pressure: 1.19E-06mmHg at 25°C
• Boiling Point: 401.3°Cat760mmHg
• Flash Point: 196.5°C
• PSA: 41.82000
• Density: 1.027g/cm³
• LogP: 4.25360
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 235.157228913
• Heavy Atom Count: 17
• Complexity: 210

Purity/Quality:

98%Min ^*data from raw suppliers

N-[4-(hexyloxy)phenyl]acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCOC1=CC=C(C=C1)NC(=O)C

Technology Process of N-[4-(hexyloxy)phenyl]acetamide

There total 4 articles about N-[4-(hexyloxy)phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-bromo-hexane (111-25-1) + 4-acetaminophenol (103-90-2,8055-08-1) → N-(4-(hexyloxy)phenyl)acetamide (41240-77-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 70 - 80 ℃; for 3h;

DOI:10.1039/c2jm30550j

Reference yield:

4-(n-hexyloxy)aniline (39905-57-2) + acetic anhydride (108-24-7) → N-(4-(hexyloxy)phenyl)acetamide (41240-77-1)

Guidance literature:

With acetic acid; In water; at 0 - 5 ℃;

DOI:10.1016/j.freeradbiomed.2013.11.025

Reference yield:

6-chloro-1-hexanol (2009-83-8) + 4-acetaminophenol (103-90-2,8055-08-1) → N-(4-(hexyloxy)phenyl)acetamide (41240-77-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; Heating;

upstream raw materials:

6-chloro-1-hexanol

4-acetaminophenol

1-bromo-6-hexanol

1-bromo-hexane

Downstream raw materials:

N,N-di(4-n-hexyloxyphenyl)amine

4-[(E)-[4-(hexyloxy)phenyl]diazenyl]phenol