Technology Process of Cyclohexanol, 1-[(1Z)-2-(tributylstannyl)ethenyl]-
There total 5 articles about Cyclohexanol, 1-[(1Z)-2-(tributylstannyl)ethenyl]- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
bis-triphenylphosphine-palladium(II) chloride;
In
tetrahydrofuran;
adding (Ph3P)2PdCl2 and alkyne to THF, cooling to 0°C, adding Bu3SnH dropwise, stirring for 1 h; concn., column chromy. (silica gel, pentane/EtOAc 95:5, 1% Et3N);
DOI:10.1021/ja0035295
- Guidance literature:
-
With
polymethylhydrosiloxane;
bis-triphenylphosphine-palladium(II) chloride;
In
tetrahydrofuran;
adding polymethylhydrosiloxane dropwise at 0°C under N2 to soln. of alkyne, Bu3SnOMe, and (PPh3)2PdCl2 in THF, stirring for 1.5 h; evapn., column chromy. (silica gel, petroleum ether/EtOAc 95:5);
DOI:10.1021/ja0035295
- Guidance literature:
-
With
polymethylhydrosiloxane; sodium methylate;
bis-triphenylphosphine-palladium(II) chloride;
In
tetrahydrofuran;
adding NaOMe and polymethylhydrosiloxane at 0°C under N2 to soln.of alkyne, Bu3SnBr, and (PPh3)2PdCl2 in dry THF, react. for 15 min; washing mixt. with water, washing org. phase with brine, drying over MgSO4, evapn., column chromy. (silica gel, petroleum ether/EtOAc 95:5);
DOI:10.1021/ja0035295
