1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[1-[(4-fluorophenyl)methyl]-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4- methyl-7-oxo-, monopotassium salt, (4R,5S,6S)-

Base Information

Chemical Name:1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[1-[(4-fluorophenyl)methyl]-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4- methyl-7-oxo-, monopotassium salt, (4R,5S,6S)-
CAS No.:878391-93-6
Molecular Formula:C20H23FN2O4S.K
Molecular Weight:444.568
Hs Code.:

1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid,
3-[[1-[(4-fluorophenyl)methyl]-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-
methyl-7-oxo-, monopotassium salt, (4R,5S,6S)-

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Chemical Property of 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[1-[(4-fluorophenyl)methyl]-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4- methyl-7-oxo-, monopotassium salt, (4R,5S,6S)-

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Technology Process of 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[1-[(4-fluorophenyl)methyl]-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4- methyl-7-oxo-, monopotassium salt, (4R,5S,6S)-

There total 3 articles about 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[1-[(4-fluorophenyl)methyl]-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4- methyl-7-oxo-, monopotassium salt, (4R,5S,6S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 4-nitrobenzyl (1R,5S,6S)-2-(1-(4-fluorobenzyl)azetidin-3-ylthio)-6-((1R)-1-hydroxyethyl)-1-methylcarbapen-2-em-3-carboxylate hydrochloride

: 878391-93-6
potassium (1R,5S,6S)-2-(1-(4-fluorobenzyl)-azetidine-3-yl-thio)-6-[(1R)-1-hydroxylethyl]-1-methylcarbapen-2-em-3-carboxylate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; at 25 - 30 ℃; for 3h; under 760.051 Torr; Aqueous phosphate buffer;