1-(5-Isoquinolinesulfonyl)-3-methylpiperazine dihydrochloride

Base Information

Chemical Name:1-(5-Isoquinolinesulfonyl)-3-methylpiperazine dihydrochloride
CAS No.:108930-17-2
Molecular Formula:C₁₄H₁₇N₃O₂S*2ClH
Molecular Weight:364.296
Hs Code.:2935009090
ChEMBL ID:CHEMBL1256679
Mol file:108930-17-2.mol

Synonyms:Isoquinoline,5-[(2-methyl-1-piperazinyl)sulfonyl]-,hydrochloride (1:2);SMR000653453;1-(5-ISOQUINOLINESULFONYL)-3-METHYLPIPERAZINE DIHYDROCHLORIDE;MLS001148107;MLS001332609;MLS001332610;MLS002172446;SCHEMBL6414754;SGCUT00138;CHEMBL1256679;AKOS025985872;Z1491263437;1-(5-isoquinolinesulfonyl)-2-methylpipera-zine hydrochloride

Suppliers and Price of 1-(5-Isoquinolinesulfonyl)-3-methylpiperazine dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
H-7 dihydrochloride
10mg
$ 389.00

TRC
1-(5-Isoquinolinesulfonyl)-2-methylpiperazineDihydrochloride
5mg
$ 65.00

Tocris
H-7 dihydrochloride ≥99%(HPLC)
10
$ 149.00

Tocris
H-7 dihydrochloride ≥99%(HPLC)
50
$ 610.00

Sigma-Aldrich
H-7 dihydrochloride ≥98% (HPLC)
25mg
$ 642.00

Sigma-Aldrich
H-7 dihydrochloride ≥98% (HPLC)
100 mg
$ 1890.00

Sigma-Aldrich
H-7 dihydrochloride ≥98% (HPLC)
5mg
$ 190.00

Sigma-Aldrich
H-7, Dihydrochloride
1mg-m
$ 130.00

Cayman Chemical
H-7 (hydrochloride) ≥98%
10mg
$ 77.00

Cayman Chemical
H-7 (hydrochloride) ≥98%
5mg
$ 45.00

Total 14 raw suppliers

Chemical Property of 1-(5-Isoquinolinesulfonyl)-3-methylpiperazine dihydrochloride

Chemical Property:

Appearance/Colour:White Crystalline Solid
Vapor Pressure:6E-10mmHg at 25°C
Melting Point:215-225 °C
Boiling Point:495.3 °C at 760 mmHg
Flash Point:253.3 °C
PSA：70.68000
LogP:4.16870
Storage Temp.:2-8°C
Solubility.:H2O: 20 mg/mL
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:327.0808257
Heavy Atom Count:21
Complexity:434

Purity/Quality:

98%min ^*data from raw suppliers

H-7 dihydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CNCCN1S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl
Uses A selective inhibitor of protein kinase C or cyclic-nucleotide-dependent protein kinases H-7 dihydrochloride has been used to study H-7-induced inhibition of contractility in rat embryo fibroblasts (REF52) cells and acts as a kinase inhibitor.

Technology Process of 1-(5-Isoquinolinesulfonyl)-3-methylpiperazine dihydrochloride

There total 1 articles about 1-(5-Isoquinolinesulfonyl)-3-methylpiperazine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: