brassilexin

Base Information

• Chemical Name: brassilexin
• CAS No.: 119752-76-0
• Molecular Formula: C₉H₆N₂S
• Molecular Weight: 174.226
• Mol file: 119752-76-0.mol

Synonyms:Brassilexin;Brassilexine

Chemical Property of brassilexin

Chemical Property:

• Vapor Pressure: 1.92E-05mmHg at 25°C
• Boiling Point: 362.6°Cat760mmHg
• Flash Point: 173.1°C
• PSA: 56.92000
• Density: 1.5g/cm³
• LogP: 2.77760
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly), Methanol (Slightly))

Purity/Quality:

98% ^*data from raw suppliers

8H-Isothiazolo[5,4-b]indole 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Brassilexin is a novel sulphur-containing phytoalexin from Brassica Juncea L.

Technology Process of brassilexin

There total 10 articles about brassilexin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-bromo-1H-indole-3-carbaldehyde (119910-45-1) → brassilexin (119752-76-0)

Guidance literature:

With sodium thiocyanide; urea; In N,N-dimethyl-formamide; at 140 ℃; for 0.05h; under 7500.75 Torr; Microwave irradiation;

DOI:10.1016/j.tetlet.2012.06.021

Reference yield: 82.0%

3-(amino)methyleneindoline-2-thione (339306-62-6) → brassilexin (119752-76-0)

Guidance literature:

With pyrographite; at 25 ℃;

DOI:10.1039/a803485k

Reference yield: 70.0%

indolin-2-thione (496-30-0) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → brassilexin (119752-76-0)

Guidance literature:

indolin-2-thione; N,N-dimethyl-formamide; With trichlorophosphate; at 40 ℃; for 1h;

With ammonium hydroxide; at 0 ℃;

With pyridine; iodine; Further stages.;

DOI:10.1021/ol015691y

upstream raw materials:

2,2'-Bis(3-hydroxyiminomethyleneindolyl)sulfide

cyclobrassinin

3-(amino)methyleneindoline-2-thione

indolin-2-thione