1-Boc-4-Cbz-Aminoazepane

Base Information

Chemical Name:1-Boc-4-Cbz-Aminoazepane
CAS No.:878630-96-7
Molecular Formula:C19H28N2O4
Molecular Weight:348.442
Hs Code.:2933990090
Mol file:878630-96-7.mol

Synonyms:(R)-tert-butyl 4-(benzyloxycarbonylamino)azepane-1-carboxylate;tert-butyl pyridazin-3-ylcarbamate;tert-butyl N-(3-pyridazinyl)carbamate;1,1-dimethylethyl 4-({[(phenylmethyl)oxy]carbonyl}amino)hexahydro-1H-azepine-1-carboxylate;1,1-dimethylethyl 3-pyridazinylcarbamate;3-(t-butoxycarbonylamino)pyridazine;

Suppliers and Price of 1-Boc-4-Cbz-Aminoazepane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-Boc-4-Cbz-aminoazepane 95+%
1g
$ 1357.00

Matrix Scientific
1-Boc-4-Cbz-aminoazepane 95+%
250mg
$ 629.00

Crysdot
1-Boc-4-Cbz-aminoazepane 97%
5g
$ 574.00

Crysdot
1-Boc-4-Cbz-aminoazepane 97%
10g
$ 861.00

Chemenu
1-Boc-4-(Cbz-amino)azepane 95+%
1g
$ 194.00

Chemenu
1-Boc-4-(Cbz-amino)azepane 95+%
10g
$ 813.00

Chemenu
1-Boc-4-(Cbz-amino)azepane 95+%
5g
$ 542.00

Biosynth Carbosynth
1-Boc-4-Cbz-aminoazepane
100 mg
$ 66.00

Biosynth Carbosynth
1-Boc-4-Cbz-aminoazepane
250 mg
$ 132.50

Biosynth Carbosynth
1-Boc-4-Cbz-aminoazepane
1 g
$ 399.00

Total 31 raw suppliers

Chemical Property of 1-Boc-4-Cbz-Aminoazepane

Chemical Property:

PSA：67.87000
LogP:4.03120
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

1-Boc-4-Cbz-aminoazepane 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Boc-4-Cbz-Aminoazepane

There total 1 articles about 1-Boc-4-Cbz-Aminoazepane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 196613-57-7
tert-butyl 4-aminoazepane-1-carboxylate

: 501-53-1,94274-21-2
benzyl chloroformate

: 878630-96-7
(R)-tert-butyl 4-(benzyloxycarbonylamino)azepane-1-carboxylate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 4h;

Reference yield:

: 878630-96-7
(R)-tert-butyl 4-(benzyloxycarbonylamino)azepane-1-carboxylate

: (R)-benzyl azepan-4-ylcarbamate

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; water; for 2h;

Reference yield:

: 878630-96-7
(R)-tert-butyl 4-(benzyloxycarbonylamino)azepane-1-carboxylate

: 1338715-74-4
(R)-5-amino-N-(5-(4-aminoazepan-1-yl)-1-methyl-1H-pyrazol-4-yl)-2-(2,4-difluorophenyl)thiazole-4-carboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogenchloride / 1,4-dioxane; water / 2 h

2: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; diisopropylethylamine / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

3: caesium carbonate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / N,N-dimethyl-formamide / 0.5 h / 100 °C / Inert atmosphere; Microwave irradiation

4: boron tribromide / dichloromethane / 20 h / -20 - 20 °C / Inert atmosphere

With hydrogenchloride; diisopropylethylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; boron tribromide; caesium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; dichloromethane; water; 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran; N,N-dimethyl-formamide; 3: Suzuki Coupling;