Benzoic acid, 4-(dimethylamino)-, (1S,2S)-2-[[4-(dimethylamino)benzoyl]oxy]-1-(2-hydroxyethyl)nonadecyl ester

Base Information

• Chemical Name: Benzoic acid, 4-(dimethylamino)-, (1S,2S)-2-[[4-(dimethylamino)benzoyl]oxy]-1-(2-hydroxyethyl)nonadecyl ester
• CAS No.: 879290-79-6
• Molecular Formula: C39H62N2O5
• Molecular Weight: 638.932
• Mol file: 879290-79-6.mol

Synonyms:

Chemical Property of Benzoic acid, 4-(dimethylamino)-, (1S,2S)-2-[[4-(dimethylamino)benzoyl]oxy]-1-(2-hydroxyethyl)nonadecyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid, 4-(dimethylamino)-, (1S,2S)-2-[[4-(dimethylamino)benzoyl]oxy]-1-(2-hydroxyethyl)nonadecyl ester

There total 6 articles about Benzoic acid, 4-(dimethylamino)-, (1S,2S)-2-[[4-(dimethylamino)benzoyl]oxy]-1-(2-hydroxyethyl)nonadecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

C47H70N2O6 (879290-78-5) → C39H62N2O5 (879290-79-6)

Guidance literature:

With water; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1021/jo052073c

Reference yield:

(E)-Henicos-3-en-1-ol (879290-72-9) → C39H62N2O5 (879290-79-6)

Guidance literature:

Multi-step reaction with 4 steps

1: NaH; TBAI / tetrahydrofuran / 18 h / 60 °C

2: 92 percent / AD-mix-α; methanesulfonamide; water / K2OsO4*2H2O / 2-methyl-propan-2-ol / 20 h / 0 °C

3: 50 percent / DMAP / CH₂Cl₂ / 15 h

4: 50 percent / DDQ; H₂O / CH₂Cl₂ / 0.5 h / 0 °C

With dmap; AD-mix-α; methanesulfonamide; water; tetra-(n-butyl)ammonium iodide; sodium hydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; potassium osmate(VI); In tetrahydrofuran; dichloromethane; tert-butyl alcohol; 2: Sharpless asymmetric dihydroxylation;

DOI:10.1021/jo052073c

Reference yield:

heneicos-3-yn-1-ol (879290-35-4) → C39H62N2O5 (879290-79-6)

Guidance literature:

Multi-step reaction with 5 steps

1: 87 percent / LAH / bis-(2-methoxy-ethyl) ether / 17 h / 125 °C

2: NaH; TBAI / tetrahydrofuran / 18 h / 60 °C

3: 92 percent / AD-mix-α; methanesulfonamide; water / K2OsO4*2H2O / 2-methyl-propan-2-ol / 20 h / 0 °C

4: 50 percent / DMAP / CH₂Cl₂ / 15 h

5: 50 percent / DDQ; H₂O / CH₂Cl₂ / 0.5 h / 0 °C

With dmap; AD-mix-α; lithium aluminium tetrahydride; methanesulfonamide; water; tetra-(n-butyl)ammonium iodide; sodium hydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; potassium osmate(VI); In tetrahydrofuran; dichloromethane; diethylene glycol dimethyl ether; tert-butyl alcohol; 3: Sharpless asymmetric dihydroxylation;

DOI:10.1021/jo052073c

upstream raw materials:

C₄₇H₇₀N₂O₆

(E)-Henicos-3-en-1-ol

heneicos-3-yn-1-ol

1-[((E)-Henicos-3-enyl)oxymethyl]-4-methoxy-benzene