N-Desmethylvinblastine

Base Information

• Chemical Name: N-Desmethylvinblastine
• CAS No.: 18172-50-4
• Molecular Formula: C₄₅H₅₆N₄O₉
• Molecular Weight: 796.961
• Mol file: 18172-50-4.mol

Synonyms:1-Demethylvincaleukoblastine;N-Deformylleurocristine; N-Deformylvincristine; N-Demethylvinblastine;N-Demethylvincaleukoblastine

Chemical Property of N-Desmethylvinblastine

Chemical Property:

• Melting Point: 186-188°C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 162.89000
• Density: 1.38g/cm³
• LogP: 3.98040
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

N-DesmethylVinblastine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Impurity C.

Technology Process of N-Desmethylvinblastine

There total 1 articles about N-Desmethylvinblastine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

vincristine dihydrogen sulphate (2068-78-2,23397-21-9,132142-73-5) → N-deformyl-4-deacetylvincristine (55324-83-9,1285859-25-7) + N-deformylvincristine (18172-50-4)

Guidance literature:

With sulfuric acid; In methanol; at 0 ℃; for 96h;

upstream raw materials:

vincristine dihydrogen sulphate