Chemical Property of Nimbolide
Chemical Property:
- Melting Point:>223°C (dec.)
- Boiling Point:608.6°Cat760mmHg
- Flash Point:321.9°C
- PSA：92.04000
- Density:1.32g/cm3
- LogP:3.59900
- Storage Temp.:Hygroscopic, -20?C Freezer, Under Inert Atmosphere
- Solubility.:Chloroform, Ethyl Acetate
- XLogP3:2.2
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:7
- Rotatable Bond Count:4
- Exact Mass:466.19915329
- Heavy Atom Count:34
- Complexity:1040
- Purity/Quality:
-
99% *data from raw suppliers
Nimbolide *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CC1=C2C(CC1C3=COC=C3)OC4C2(C(C5(C6C4OC(=O)C6(C=CC5=O)C)C)CC(=O)OC)C
- Isomeric SMILES:CC1=C2[C@@H](C[C@H]1C3=COC=C3)O[C@H]4[C@@]2([C@@H]([C@@]5([C@H]6[C@H]4OC(=O)[C@@]6(C=CC5=O)C)C)CC(=O)OC)C
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Uses
Nimbolide, a natural triterpenoid present in the edible parts of the neem tree (Azadirachta indica), was found to be growth-inhibitory in human colon carcinoma HT-29 cells. Nimbolide treatment of cells at 2.5 - 10 μM resulted in moderate to very strong growth inhibition. Nimbolide, a natural triterpenoid present in the edible parts of the neem tree (Azadirachta indica), was found to be growth-inhibitory in human colon carcinoma HT-29 cells. Nimbolide treatment of cells at 2.5 - 10 μM resulted in moderate to very strong gr
