(2R,6R)-2-(2-methoxyphenyl)-6-methyloxan-4-one

Base Information

Chemical Name:(2R,6R)-2-(2-methoxyphenyl)-6-methyloxan-4-one
CAS No.:88083-99-2
Molecular Formula:C₁₃H₁₆O₃
Molecular Weight:220.268
Hs Code.:
DSSTox Substance ID:DTXSID20520750
Wikidata:Q82384837

Synonyms:88083-99-2;(2R,6R)-2-(2-methoxyphenyl)-6-methyloxan-4-one;DTXSID20520750

Suppliers and Price of (2R,6R)-2-(2-methoxyphenyl)-6-methyloxan-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (2R,6R)-2-(2-methoxyphenyl)-6-methyloxan-4-one

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:220.109944368
Heavy Atom Count:16
Complexity:252

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC(=O)CC(O1)C2=CC=CC=C2OC
Isomeric SMILES:C[C@@H]1CC(=O)C[C@@H](O1)C2=CC=CC=C2OC

Technology Process of (2R,6R)-2-(2-methoxyphenyl)-6-methyloxan-4-one

There total 3 articles about (2R,6R)-2-(2-methoxyphenyl)-6-methyloxan-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 88083-98-1,94110-19-7
cis-2-methyl-6-(o-methoxyphenyl)-4-((triethylsilyl)oxy)-5,6-dihydro-2H-pyran

: 88083-99-2,94110-20-0
cis-2-(o-methoxyphenyl)-6-methyltetrahydro-4H-pyran-4-one

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; for 0.666667h; Ambient temperature;
DOI:10.1021/ja00291a031

Reference yield:

: 88083-96-9
(3E)-2-triethylsilyloxy-1,3-pentadiene

: 88083-99-2,94110-20-0
cis-2-(o-methoxyphenyl)-6-methyltetrahydro-4H-pyran-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / Eu(fod)3 / CHCl₃ / 12 h / 65 °C

2: 90 percent / HCl (1N) / tetrahydrofuran / 0.67 h / Ambient temperature

With hydrogenchloride; Eu(fod)3; In tetrahydrofuran; chloroform;
DOI:10.1021/ja00291a031

Reference yield:

: 3102-33-8
trans-3-penten-2-one

: 88083-99-2,94110-20-0
cis-2-(o-methoxyphenyl)-6-methyltetrahydro-4H-pyran-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / lithium diisopropylamide (LDA) / tetrahydrofuran / 2.5 h / -78 - 20 °C

2: 86 percent / Eu(fod)3 / CHCl₃ / 12 h / 65 °C

3: 90 percent / HCl (1N) / tetrahydrofuran / 0.67 h / Ambient temperature

With hydrogenchloride; lithium diisopropyl amide; Eu(fod)3; In tetrahydrofuran; chloroform;
DOI:10.1021/ja00291a031