2-amino-3-(2-amino-2-carboxy-ethyl)selanylselanyl-propanoic acid

Base Information

• Chemical Name: 2-amino-3-(2-amino-2-carboxy-ethyl)selanylselanyl-propanoic acid
• CAS No.: 1464-43-3
• Molecular Formula: C₆H₁₂N₂O₄Se₂
• Molecular Weight: 334.092
• Mol file: 1464-43-3.mol

Synonyms:3,3-Diselenobisalanine;3,3-Diselenodialanine;Alanine, 3,3-diselenobis- (9CI);2-amino-3-(2-amino-2-carboxy-ethyl)selanylselanyl-propanoic acid;ALANINE, 3,3-DISELENODI-;Selenocystine;3,3′-DISELENODIALANINE;3,3′-DISELENODI-ALANINE;ALANINE, 3,3′-DISELENOBIS-(9CI);

Chemical Property of 2-amino-3-(2-amino-2-carboxy-ethyl)selanylselanyl-propanoic acid

Chemical Property:

• Vapor Pressure: 5.12E-13mmHg at 25°C
• Boiling Point: 538.3°Cat760mmHg
• Flash Point: 279.3°C
• PSA: 126.64000
• Density: g/cm³
• LogP: -0.62920

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-amino-3-(2-amino-2-carboxy-ethyl)selanylselanyl-propanoic acid

There total 28 articles about 2-amino-3-(2-amino-2-carboxy-ethyl)selanylselanyl-propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

β-chloro-L-alanine hydrochloride (51887-89-9,3157-46-8) → seleno-L-cystine (1464-43-3,2897-21-4,26932-45-6,29621-88-3)

Guidance literature:

With selenium; sodium tetrahydroborate; at 37 ℃; pH=9;

DOI:10.1016/S0960-894X(01)00590-X

Reference yield: 84.0%

L-dibenzyl N,N'-di(benzyloxycarbonyl)selenocystinate (109276-78-0) → seleno-L-cystine (1464-43-3,2897-21-4,26932-45-6,29621-88-3)

Guidance literature:

With hydrogen bromide; In acetic acid; for 2h; Ambient temperature;

DOI:10.1016/S0040-4020(01)88049-2

Reference yield: 82.0%

dimethyl 3,3'-diselanediyl-(2R,2'R)-bis(2-((tertbutoxycarbonyl)amino)propanoate) (195324-31-3) → seleno-L-cystine (1464-43-3,2897-21-4,26932-45-6,29621-88-3)

Guidance literature:

dimethyl 3,3'-diselanediyl-(2R,2'R)-bis(2-((tertbutoxycarbonyl)amino)propanoate); With water; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;

With hydrogenchloride; at 75 ℃; for 12h; Further stages.;

DOI:10.1021/ol015712o

upstream raw materials:

(2R)-serine O-sulfate

O-acetyl-D-serine

Se-benzyl-L-selenocysteine

L-dibenzyl N,N'-di(benzyloxycarbonyl)selenocystinate

Downstream raw materials:

selenocysteine

L-selenocysteine

(2R,2'R)-3,3'-diselanediylbis(2-((tert-butoxycarbonyl)amino)propanoic acid)

Oxidized glutathione