Technology Process of pregnane-3,6,17-triol triacetate
There total 6 articles about pregnane-3,6,17-triol triacetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 400 mg / H2CrO4 / acetic acid / 2 h
2: lithium tri-t-butoxyaluminium hydride (LTBA) / tetrahydrofuran / 1 h / 0 °C
3: 1.85 g / H2 / 5percent Pd/CaCO3 / pyridine / 18 h
4: 1.) LS-Selectride / 1.) THF, -78 deg C; 2.) pyridine, room temp.
With
lithium tri(t-butoxy)aluminum hydride; hydrogen; chromic acid; lithium tri-sec-butyl(hydrido)borate;
Lindlar's catalyst;
In
tetrahydrofuran; pyridine; acetic acid;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: lithium tri-t-butoxyaluminium hydride (LTBA) / tetrahydrofuran / 1 h / 0 °C
2: 1.85 g / H2 / 5percent Pd/CaCO3 / pyridine / 18 h
3: 1.) LS-Selectride / 1.) THF, -78 deg C; 2.) pyridine, room temp.
With
lithium tri(t-butoxy)aluminum hydride; hydrogen; lithium tri-sec-butyl(hydrido)borate;
Lindlar's catalyst;
In
tetrahydrofuran; pyridine;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.85 g / H2 / 5percent Pd/CaCO3 / pyridine / 18 h
2: 1.) LS-Selectride / 1.) THF, -78 deg C; 2.) pyridine, room temp.
With
hydrogen; lithium tri-sec-butyl(hydrido)borate;
Lindlar's catalyst;
In
pyridine;
