N(4)-(4-Carboxybutyryl)-1-beta-arabinofuranosylcytosine

Base Information

Chemical Name:N(4)-(4-Carboxybutyryl)-1-beta-arabinofuranosylcytosine
CAS No.:55726-38-0
Molecular Formula:C₁₄H₁₉N₃O₈
Molecular Weight:357.32
Hs Code.:
DSSTox Substance ID:DTXSID50971094
Mol file:55726-38-0.mol

Synonyms:glu-ara-C;N(4)-(4-carboxybutyryl)-1-beta-arabinofuranosylcytosine;N4-(4-carboxybutyryl)-ara-C

Suppliers and Price of N(4)-(4-Carboxybutyryl)-1-beta-arabinofuranosylcytosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N(4)-(4-Carboxybutyryl)-1-beta-arabinofuranosylcytosine

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：171.21000
Density:1.71g/cm³
LogP:-1.87880
XLogP3:-1.6
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:7
Exact Mass:357.11721457
Heavy Atom Count:25
Complexity:605

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN(C(=O)N=C1NC(=O)CCCC(=O)O)C2C(C(C(O2)CO)O)O
Isomeric SMILES:C1=CN(C(=O)N=C1NC(=O)CCCC(=O)O)C2[C@H]([C@@H]([C@H](O2)CO)O)O

Technology Process of N(4)-(4-Carboxybutyryl)-1-beta-arabinofuranosylcytosine

There total 4 articles about N(4)-(4-Carboxybutyryl)-1-beta-arabinofuranosylcytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-trityloxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-ylcarbamoyl]-butyric acid

: 55726-38-0
N⁴-(4-carboxybutyryl)-1-β-D-arabinofuranosylcytosine

Guidance literature:: With acetic acid; at 90 ℃; for 0.166667h; Yield given;
DOI:10.1248/cpb.37.1587

Reference yield:

: 108-55-4
glutaric anhydride,

: 55726-38-0
N⁴-(4-carboxybutyryl)-1-β-D-arabinofuranosylcytosine

Guidance literature:: Multi-step reaction with 2 steps

1: dioxane / 168 h / Ambient temperature

2: 50 percent (v/v) aqueous acetic acid / 0.17 h / 90 °C

With acetic acid; In 1,4-dioxane;
DOI:10.1248/cpb.37.1587

Reference yield:

: 7075-13-0
1-(5'-o-trityl-β-D-arabinofuranosyl)cytosine

: 55726-38-0
N⁴-(4-carboxybutyryl)-1-β-D-arabinofuranosylcytosine

Guidance literature:: Multi-step reaction with 2 steps

1: dioxane / 168 h / Ambient temperature

2: 50 percent (v/v) aqueous acetic acid / 0.17 h / 90 °C

With acetic acid; In 1,4-dioxane;
DOI:10.1248/cpb.37.1587