N-(5-(p-Aminophenoxy)pentyl)-2,2-dichloroacetamide

Base Information

• Chemical Name: N-(5-(p-Aminophenoxy)pentyl)-2,2-dichloroacetamide
• CAS No.: 101264-04-4
• Molecular Formula: C₁₃H₁₈Cl₂N₂O₂
• Molecular Weight: 305.204
• Mol file: 101264-04-4.mol

Synonyms:Acetamide,N-[5-(p-aminophenoxy)pentyl]-2,2-dichloro- (6CI)

Chemical Property of N-(5-(p-Aminophenoxy)pentyl)-2,2-dichloroacetamide

Chemical Property:

• Vapor Pressure: 1.85E-10mmHg at 25°C
• Boiling Point: 508.5°Cat760mmHg
• Flash Point: 261.3°C
• PSA: 67.84000
• Density: 1.251g/cm³
• LogP: 4.15930

Purity/Quality:

N-(5-(PARA-AMINOPHENOXY)PENTYL)-2,2-DICHLOROACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(5-(p-Aminophenoxy)pentyl)-2,2-dichloroacetamide

There total 4 articles about N-(5-(p-Aminophenoxy)pentyl)-2,2-dichloroacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(4-nitro-phenoxy)-pentylamine (99982-26-0) → dichloro-acetic acid-[5-(4-amino-phenoxy)-pentylamide] (101264-04-4)

Guidance literature:

Multi-step reaction with 2 steps

1: Fe / aq. acetic acid

2: methanol

With iron; In methanol; acetic acid;

DOI:10.1039/jr9620001420

Reference yield:

2-[5-(4-aminophenoxy)pentyl]-1H isoindole 1,3-(2H)-dione (1673-06-9) → dichloro-acetic acid-[5-(4-amino-phenoxy)-pentylamide] (101264-04-4)

Guidance literature:

Multi-step reaction with 2 steps

1: N₂H₄

With hydrazine;

Reference yield:

dichloroacetic acid methyl ester (116-54-1) + 4-(5-amino-pentyloxy)-aniline (91215-95-1) → dichloro-acetic acid-[5-(4-amino-phenoxy)-pentylamide] (101264-04-4)

Guidance literature:

In methanol;

DOI:10.1039/jr9620001420

upstream raw materials:

4-(5-amino-pentyloxy)-aniline

ethyl 1,1-dichloroacetate

dichloroacetic acid methyl ester

2-[5-(4-aminophenoxy)pentyl]-1H isoindole 1,3-(2H)-dione