METHYL 2-CYANO-3-METHOXYCROTONATE

Base Information

• Chemical Name: METHYL 2-CYANO-3-METHOXYCROTONATE
• CAS No.: 89776-71-6
• Molecular Formula: C7H9NO3
• Molecular Weight: 155.15100
• Hs Code.: 2926909090
• Mol file: 89776-71-6.mol

Synonyms:METHYL 2-CYANO-3-METHOXYBUT-2-ENOATE;METHYL 2-CYANO-3-METHOXYCROTONATE;2-Cyan-3-methoxy-crotonsaeure-methylester;2-cyano-3-methoxy-crotonic acid methyl ester;

Chemical Property of METHYL 2-CYANO-3-METHOXYCROTONATE

Chemical Property:

• PSA: 59.32000
• LogP: 0.60338

Purity/Quality:

98%min ^*data from raw suppliers

Methyl2-Cyano-3-methoxycrotonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 2-CYANO-3-METHOXYCROTONATE

There total 3 articles about METHYL 2-CYANO-3-METHOXYCROTONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-cyano-acetoacetic acid tert-butyl ester (57847-26-4) → methyl-2-cyano-3-methoxybut-2-enoate (89776-71-6)

Guidance literature:

Multi-step reaction with 2 steps

1: TsOH / benzene / Heating

2: diethyl ether

With toluene-4-sulfonic acid; In diethyl ether; benzene;

DOI:10.1002/hlca.19640470605

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 2-cyano-3-oxobutanoic acid methyl ester (3288-52-6) → methyl-2-cyano-3-methoxybut-2-enoate (89776-71-6)

Guidance literature:

With diethyl ether; at -10 ℃; higher-melting form of <1-methoxy-ethylidene>-cyanoacetic acid methyl ester;

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + α-Cyan-acetessigsaeure (88511-40-4) → methyl-2-cyano-3-methoxybut-2-enoate (89776-71-6)

Guidance literature:

In diethyl ether;

DOI:10.1002/hlca.19640470605

upstream raw materials:

diazomethane

2-cyano-3-oxobutanoic acid methyl ester

α-Cyan-acetessigsaeure

2-cyano-acetoacetic acid tert-butyl ester

Downstream raw materials:

2-cyano-3-oxobutanoic acid methyl ester