Oxiranecarbonyl azide, 3-methyl-3-phenyl-, trans-

Base Information

• Chemical Name: Oxiranecarbonyl azide, 3-methyl-3-phenyl-, trans-
• CAS No.: 89849-04-7
• Molecular Formula: C₁₀H₉N₃O₂
• Molecular Weight: 203.2
• Mol file: 89849-04-7.mol

Synonyms:

Chemical Property of Oxiranecarbonyl azide, 3-methyl-3-phenyl-, trans-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Oxiranecarbonyl azide, 3-methyl-3-phenyl-, trans-

There total 2 articles about Oxiranecarbonyl azide, 3-methyl-3-phenyl-, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3R)-3-Methyl-3-phenyl-oxirane-2-carbonyl chloride (76527-42-9) → (2R,3S)-3-Methyl-3-phenyl-oxirane-2-carbonyl azide (89849-04-7)

Guidance literature:

With pyridine; hydrogen azide; In diethyl ether; benzene; for 1h; Yield given; -20 to 10 deg C;

DOI:10.1021/jo00186a030

Reference yield:

Sodium; (2S,3R)-3-methyl-3-phenyl-oxirane-2-carboxylate (54984-42-8) → (2R,3S)-3-Methyl-3-phenyl-oxirane-2-carbonyl azide (89849-04-7)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl chloride, pyridine / tetrahydrofuran / 1 h / Ambient temperature

2: hydrazoic acid, pyridine / diethyl ether; benzene / 1 h / -20 to 10 deg C

With pyridine; hydrogen azide; oxalyl dichloride; In tetrahydrofuran; diethyl ether; benzene;

DOI:10.1021/jo00186a030

upstream raw materials:

(2S,3R)-3-Methyl-3-phenyl-oxirane-2-carbonyl chloride

Sodium; (2S,3R)-3-methyl-3-phenyl-oxirane-2-carboxylate