4-propyl-2-Pyrrolidinone

Base Information

• Chemical Name: 4-propyl-2-Pyrrolidinone
• CAS No.: 89895-19-2
• Molecular Formula: C7H13NO
• Molecular Weight: 127.186
• Hs Code.: 2933790090
• Mol file: 89895-19-2.mol

Synonyms:4-propyl-pyridine-2-carboxylic acid ethyl ester;2-Pyridinecarboxylic acid,4-propyl-,ethyl ester;4-propyl-pyrrolidin-2-one;4-Propyl-pyridin-2-carbonsaeure-aethylester;3-Propyl-pyrrolidon-(5);

Chemical Property of 4-propyl-2-Pyrrolidinone

Chemical Property:

• Boiling Point: 263.4±9.0 °C(Predicted)
• PKA: 16.66±0.40(Predicted)
• PSA: 29.10000
• Density: 0.939±0.06 g/cm3(Predicted)
• LogP: 1.25140

Purity/Quality:

97% ^*data from raw suppliers

4-Propylpyrrolidin-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-propyl-2-Pyrrolidinone

There total 27 articles about 4-propyl-2-Pyrrolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.7%

3-nitromethyl-hexanoic acid ethyl ester (128013-61-6) → 4-propyl-2-pyrrolidinone (89895-19-2)

Guidance literature:

With hydrogen; Ni Raney; In methanol; at 55 ℃; for 28h; under 37503.8 Torr;

Reference yield: 12.0%

N-(4-methoxybenzyl)-4-propyl-2-pyrrolidinone → 4-propyl-2-pyrrolidinone (89895-19-2)

Guidance literature:

With ammonium cerium (IV) nitrate; water; In acetonitrile; at 21 ℃;

DOI:10.1002/adsc.201701449

Reference yield:

methyl 3-(nitromethyl)hexanoate → 4-propyl-2-pyrrolidinone (89895-19-2)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol;

DOI:10.1016/j.bmcl.2004.06.033

upstream raw materials:

2-oxo-4-propyl-pyrrolidine-3-carboxylic acid

methyl (E)-hex-2-enoate

2-oxo-4-propyl-pyrrolidine-3-carboxylic acid ethyl ester

3-nitromethyl-hexanoic acid ethyl ester