3,4-dimethoxy-5-propoxyBenzaldehyde

Base Information

• Chemical Name: 3,4-dimethoxy-5-propoxyBenzaldehyde
• CAS No.: 90132-19-7
• Molecular Formula: C12H16O4
• Molecular Weight: 224.257
• DSSTox Substance ID: DTXSID30598389
• Wikidata: Q82494139
• Mol file: 90132-19-7.mol

Synonyms:90132-19-7;3,4-dimethoxy-5-propoxyBenzaldehyde;SCHEMBL7844422;DTXSID30598389;DA-01319

Chemical Property of 3,4-dimethoxy-5-propoxyBenzaldehyde

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 224.10485899
• Heavy Atom Count: 16
• Complexity: 207

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCOC1=CC(=CC(=C1OC)OC)C=O

Technology Process of 3,4-dimethoxy-5-propoxyBenzaldehyde

There total 1 articles about 3,4-dimethoxy-5-propoxyBenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3-hydroxy-4,5-dimethoxybenzaldehyde (29865-90-5) + propyl bromide (106-94-5) → 3,4-dimrthoxy-5-n-propoxybenzaldehyde (90132-19-7)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; for 0.25h; Heating;

DOI:10.1021/jm00373a013

Reference yield: 53.0%

nitromethane (75-52-5) + 3,4-dimrthoxy-5-n-propoxybenzaldehyde (90132-19-7) → 1,2-Dimethoxy-5-((E)-2-nitro-vinyl)-3-propoxy-benzene (90132-24-4)

Guidance literature:

With ammonium acetate; for 1h; Heating;

DOI:10.1021/jm00373a013

Reference yield:

3,4-dimrthoxy-5-n-propoxybenzaldehyde (90132-19-7) → 2-(3,4-Dimethoxy-5-propoxy-phenyl)-ethylamine (90132-33-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 53 percent / ammonium acetate / 1 h / Heating

2: AlH₃ / tetrahydrofuran / 0.5 h / Heating

With aluminium hydride; ammonium acetate; In tetrahydrofuran;

DOI:10.1021/jm00373a013

upstream raw materials:

3-hydroxy-4,5-dimethoxybenzaldehyde

propyl bromide

Downstream raw materials:

1,2-Dimethoxy-5-((E)-2-nitro-vinyl)-3-propoxy-benzene

2-(3,4-Dimethoxy-5-propoxy-phenyl)-ethylamine