5-Bromo-2-methoxybenzene-1-thiol

Base Information

Chemical Name:5-Bromo-2-methoxybenzene-1-thiol
CAS No.:90150-99-5
Molecular Formula:C7H7BrOS
Molecular Weight:219.102
Hs Code.:
European Community (EC) Number:832-966-1
DSSTox Substance ID:DTXSID901307195
Nikkaji Number:J1.928.149C

Synonyms:5-bromo-2-methoxybenzene-1-thiol;90150-99-5;5-BROMO-2-METHOXYBENZENETHIOL;Benzenethiol, 5-bromo-2-methoxy-;5-Bromo-2-methoxythiophenol;SCHEMBL47014;2-methoxy-5-bromo-thiophenol;NVWMBFHESONALO-UHFFFAOYSA-N;DTXSID901307195;EN300-85417;Z367661854

Suppliers and Price of 5-Bromo-2-methoxybenzene-1-thiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5-Bromo-2-methoxybenzene-1-thiol

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:217.94010
Heavy Atom Count:10
Complexity:110

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)Br)S

Technology Process of 5-Bromo-2-methoxybenzene-1-thiol

There total 4 articles about 5-Bromo-2-methoxybenzene-1-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 3-(5-bromo-2-methoxyphenyl)-sulfanyl-propionic acid methyl ester

: 90150-99-5
4-methoxy-3-thio-bromobenzene

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at -78 ℃; for 0.166667h;
DOI:10.1021/jo034013h

Reference yield:

: 104-92-7
1-bromo-4-methoxy-benzene

: 90150-99-5
4-methoxy-3-thio-bromobenzene

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / -35 - 20 °C

2: Et₃N / tetrahydrofuran / 12 h / 20 °C

3: 93 percent / t-BuOK / tetrahydrofuran / 0.17 h / -78 °C

With potassium tert-butylate; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo034013h

Reference yield:

: (5-bromo-2-methoxy-phenyl)-bis-(2-methoxycarbonyl-ethyl)-sulfonium; trifluoro-methanesulfonate

: 90150-99-5
4-methoxy-3-thio-bromobenzene

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / tetrahydrofuran / 12 h / 20 °C

2: 93 percent / t-BuOK / tetrahydrofuran / 0.17 h / -78 °C

With potassium tert-butylate; triethylamine; In tetrahydrofuran;
DOI:10.1021/jo034013h