8-Methyl-9H-purine

Base Information

• Chemical Name: 8-Methyl-9H-purine
• CAS No.: 934-33-8
• Molecular Formula: C6H6 N4
• Molecular Weight: 134.14
• Hs Code.: 2933990090
• NSC Number: 22735
• DSSTox Substance ID: DTXSID00281731
• Nikkaji Number: J101.155C
• Wikidata: Q82015785
• Mol file: 934-33-8.mol

Synonyms:8-Methyl-9H-purine;934-33-8;8-Methyl-7H-purine;8-Methyl-1H-purine;1H-Purine, 8-methyl-;8-Methylpurine;Purine, 8-methyl-;1H-Purine,8-methyl-;NSC22735;8-Methyl-7H-purine #;SCHEMBL375955;DTXSID00281731;UZQYFLWZKIMYKS-UHFFFAOYSA-N;MFCD01646144;NSC-22735;AKOS016003974;AKOS025395539;AB09598;FS-6575;9H-Purine,8-methyl;Purine,8-methyl;CS-0152740;E74385;F11876;A859783

Chemical Property of 8-Methyl-9H-purine

Chemical Property:

• Vapor Pressure: 9.59E-06mmHg at 25°C
• Refractive Index: 1.7000 (estimate)
• Boiling Point: 383.6°Cat760mmHg
• Flash Point: 196.7°C
• PSA: 54.46000
• Density: 1.371g/cm³
• LogP: 0.66130
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: 52.63g/L(20 oC)
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 134.059246208
• Heavy Atom Count: 10
• Complexity: 127

Purity/Quality:

97% ^*data from raw suppliers

8-Methyl-9H-purine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NC2=NC=NC=C2N1

Technology Process of 8-Methyl-9H-purine

There total 8 articles about 8-Methyl-9H-purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-(1-Ethoxyethyl-1)-6-methylthiopurine (85110-41-4) → 2-methylbenzoimidazole (934-33-8) + 8-methyl6-methylthiopurine (1008-51-1) + 4,5-diamino-6-methylthiopyrimidine (6965-92-0) + 6-methylthiopurine (50-66-8) + 9-(1-ethoxyethyl)hypoxanthine

Guidance literature:

With sodium hydroxide; In water; at 80.1 ℃; Product distribution; Rate constant; other temperatures; alkalyne hydrolysis of 6-substituted 9-(1-ethoxyethyl)purines, effect of substituent, formation of intermediates;

Reference yield:

9-(1-ethoxyethyl)-9H-purine (78105-09-6) → 4,5-pyrimidinediamine (13754-19-3) + 2-methylbenzoimidazole (934-33-8)

Guidance literature:

With sodium hydroxide; In water; at 60.1 ℃; Product distribution; Rate constant; other temperatures; alkalyne hydrolysis of 6-substituted 9-(1-ethoxyethyl)purines, effect of substituent, formation of intermediates;

Reference yield:

9-(1-methoxyethyl)purine (95103-63-2) → 4,5-pyrimidinediamine (13754-19-3) + 2-methylbenzoimidazole (934-33-8) + 7,8-dihydro-8-methylpurine

Guidance literature:

With sodium hydroxide; at 70.1 ℃; Rate constant;

DOI:10.3891/acta.chem.scand.38b-0573

upstream raw materials:

9-(1-Ethoxyethyl-1)-6-methylthiopurine

9-(1-methoxyethyl)purine

9-(1-ethoxyethyl)-9H-purine

9-(1-Isopropoxy-ethyl)-9H-purine