3-(4-methoxyphenyl)oxirane-2-carboxylic Acid

Base Information

Chemical Name:3-(4-methoxyphenyl)oxirane-2-carboxylic Acid
CAS No.:90278-52-7
Molecular Formula:C10H10O4
Molecular Weight:194.187
Hs Code.:
DSSTox Substance ID:DTXSID50392846

Synonyms:3-(4-methoxyphenyl)oxirane-2-carboxylic Acid;90278-52-7;SCHEMBL6229779;3-(-methoxyphenyl)glycidic acid;DTXSID50392846;CHEBI:193987;PD135983;3-(4-methoxyphenyl)oxirane-2-carboxylicAcid;A916548

Suppliers and Price of 3-(4-methoxyphenyl)oxirane-2-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-(4-methoxyphenyl)oxirane-2-carboxylic Acid

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:194.05790880
Heavy Atom Count:14
Complexity:220

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2C(O2)C(=O)O

Technology Process of 3-(4-methoxyphenyl)oxirane-2-carboxylic Acid

There total 1 articles about 3-(4-methoxyphenyl)oxirane-2-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 42245-42-1
methyl 3-(4-methoxyphenyl)glycidate

: 90278-52-7
2,3-epoxy-3-(4-methoxy-phenyl)-propionic acid

Guidance literature:: With Fmoc-GFFYGHY coated on glass slide coated beforehand with poly(ethyleneimine)/poly(styrenesulfonate)/alkaline phosphate from bovineinstestinal muscosa; Flow reactor;
DOI:10.1002/anie.201909424

Reference yield:

: 90278-52-7
2,3-epoxy-3-(4-methoxy-phenyl)-propionic acid

: C₁₀H₉O₄^(1-)*K⁽¹⁺⁾

Guidance literature:: 2,3-epoxy-3-(4-methoxy-phenyl)-propionic acid; With (S)-1-phenyl-ethylamine; In di-isopropyl ether; at 20 ℃; for 2h; Cooling with ice;

With potassium hydroxide; In ethanol; for 1h; Solvent;

Reference yield:

: 90278-52-7
2,3-epoxy-3-(4-methoxy-phenyl)-propionic acid

: 220736-25-4,259794-13-3
(4R,5R)-cytoxazone

Guidance literature:: Multi-step reaction with 4 steps

1.1: (S)-1-phenyl-ethylamine / di-isopropyl ether / 2 h / 20 °C / Cooling with ice

1.2: 1 h

2.1: cobalt(II) chloride; sodium azide / water / 25 - 30 °C

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 70 °C

4.1: dichloromethane / 0 °C

With lithium aluminium tetrahydride; sodium azide; (S)-1-phenyl-ethylamine; cobalt(II) chloride; In tetrahydrofuran; dichloromethane; di-isopropyl ether; water;