Technology Process of 3-(4-methoxyphenyl)oxirane-2-carboxylic Acid
There total 1 articles about 3-(4-methoxyphenyl)oxirane-2-carboxylic Acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Fmoc-GFFYGHY coated on glass slide coated beforehand with poly(ethyleneimine)/poly(styrenesulfonate)/alkaline phosphate from bovineinstestinal muscosa;
Flow reactor;
DOI:10.1002/anie.201909424
- Guidance literature:
-
2,3-epoxy-3-(4-methoxy-phenyl)-propionic acid;
With
(S)-1-phenyl-ethylamine;
In
di-isopropyl ether;
at 20 ℃;
for 2h;
Cooling with ice;
With
potassium hydroxide;
In
ethanol;
for 1h;
Solvent;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: (S)-1-phenyl-ethylamine / di-isopropyl ether / 2 h / 20 °C / Cooling with ice
1.2: 1 h
2.1: cobalt(II) chloride; sodium azide / water / 25 - 30 °C
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 70 °C
4.1: dichloromethane / 0 °C
With
lithium aluminium tetrahydride; sodium azide; (S)-1-phenyl-ethylamine; cobalt(II) chloride;
In
tetrahydrofuran; dichloromethane; di-isopropyl ether; water;
