alpha-acetamido-N-(4-fluorobenzyl)-alpha-(furan-2-yl)acetamide

Base Information

• Chemical Name: alpha-acetamido-N-(4-fluorobenzyl)-alpha-(furan-2-yl)acetamide
• CAS No.: 124421-36-9
• Molecular Formula: C₁₅H₁₅FN₂O₃
• Molecular Weight: 290.294
• Mol file: 124421-36-9.mol

Synonyms:2-Furanacetamide,a-(acetylamino)-N-[(4-fluorophenyl)methyl]-,(?à)-

Chemical Property of alpha-acetamido-N-(4-fluorobenzyl)-alpha-(furan-2-yl)acetamide

Chemical Property:

• Vapor Pressure: 1.78E-12mmHg at 25°C
• Boiling Point: 557.8°Cat760mmHg
• PKA: 13.76±0.46(Predicted)
• Flash Point: 291.1°C
• PSA: 78.32000
• Density: 1.25g/cm³
• LogP: 3.59290

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of alpha-acetamido-N-(4-fluorobenzyl)-alpha-(furan-2-yl)acetamide

There total 2 articles about alpha-acetamido-N-(4-fluorobenzyl)-alpha-(furan-2-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-α-acetamido-2-furanacetic acid (117422-81-8) + para-fluorobenzylamine (140-75-0) → α-acetamido-N-(4-fluorobenzyl)-α-(furan-2-yl)acetamide (124421-36-9)

Guidance literature:

With 4-methyl-morpholine; isobutyl chloroformate; Yield given. Multistep reaction; 1.) THF, 5 min, 2.) RT, 5 min;

DOI:10.1021/jm00165a006

Reference yield:

→ α-acetamido-N-(4-fluorobenzyl)-α-(furan-2-yl)acetamide (124421-36-9)

Guidance literature:

upstream raw materials:

D-α-acetamido-2-furanacetic acid

para-fluorobenzylamine