4-(o-Bromobenzylidene)-1-((p-chlorobenzylidene)amino)-2-phenyl-2-imidazolin-5-one

Base Information

• Chemical Name: 4-(o-Bromobenzylidene)-1-((p-chlorobenzylidene)amino)-2-phenyl-2-imidazolin-5-one
• CAS No.: 126293-43-4
• Molecular Formula: C₂₃H₁₅BrClN₃O
• Molecular Weight: 464.749
• Mol file: 126293-43-4.mol

Synonyms:4-(o-Bromobenzylidene)-1-((p-chlorobenzylidene)amino)-2-phenyl-2-imidazolin-5-one;2-Imidazolin-5-one, 4-(o-bromobenzylidene)-1-((p-chlorobenzylidene)amino)-2-phenyl-;4H-Imidazol-4-one, 3,5-dihydro-5-((2-bromophenyl)methylene)-3-(((4-chlorophenyl)methylene)amino)-2-phenyl-;126293-43-4;LS-79871

Chemical Property of 4-(o-Bromobenzylidene)-1-((p-chlorobenzylidene)amino)-2-phenyl-2-imidazolin-5-one

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.662
• Boiling Point: 575.1°Cat760mmHg
• Flash Point: 301.6°C
• Density: 1.41g/cm³
• XLogP3: 6.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 463.00870
• Heavy Atom Count: 29
• Complexity: 678

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC(=CC3=CC=CC=C3Br)C(=O)N2N=CC4=CC=C(C=C4)Cl
• Isomeric SMILES: C1=CC=C(C=C1)C2=N/C(=C\C3=CC=CC=C3Br)/C(=O)N2/N=C/C4=CC=C(C=C4)Cl

Technology Process of 4-(o-Bromobenzylidene)-1-((p-chlorobenzylidene)amino)-2-phenyl-2-imidazolin-5-one

There total 4 articles about 4-(o-Bromobenzylidene)-1-((p-chlorobenzylidene)amino)-2-phenyl-2-imidazolin-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

N-{(Z)-2-(2-Bromo-phenyl)-1-[1-(4-chloro-phenyl)-meth-(E)-ylidene-hydrazinocarbonyl]-vinyl}-benzamide (126244-85-7) → 5-[1-(2-Bromo-phenyl)-meth-(Z)-ylidene]-3-{[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amino}-2-phenyl-3,5-dihydro-imidazol-4-one (126293-43-4)

Guidance literature:

With trichlorophosphate; In chloroform; at 40 ℃; for 2h;

Reference yield:

4-chlorobenzaldehyde (104-88-1) → 5-[1-(2-Bromo-phenyl)-meth-(Z)-ylidene]-3-{[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amino}-2-phenyl-3,5-dihydro-imidazol-4-one (126293-43-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / glacial acetic acid / ethanol / 2 h / Heating

2: 69 percent / POCl₃ / CHCl₃ / 2 h / 40 °C

With acetic acid; trichlorophosphate; In ethanol; chloroform;

Reference yield:

(2-bromobenzylidene)-2-phenyloxazol-5-one → 5-[1-(2-Bromo-phenyl)-meth-(Z)-ylidene]-3-{[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amino}-2-phenyl-3,5-dihydro-imidazol-4-one (126293-43-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / hydrazine hydrate / ethanol / Heating

2: 78 percent / glacial acetic acid / ethanol / 2 h / Heating

3: 69 percent / POCl₃ / CHCl₃ / 2 h / 40 °C

With hydrazine hydrate; acetic acid; trichlorophosphate; In ethanol; chloroform;

upstream raw materials:

N-{(Z)-2-(2-Bromo-phenyl)-1-[1-(4-chloro-phenyl)-meth-(E)-ylidene-hydrazinocarbonyl]-vinyl}-benzamide

4-chlorobenzaldehyde

N-[(Z)-2-(2-Bromo-phenyl)-1-hydrazinocarbonyl-vinyl]-benzamide