Dimethyl 2-[1-(2-aminophenyl)-1H-pyrazol-3-yl]butanedioate

Base Information

Chemical Name:Dimethyl 2-[1-(2-aminophenyl)-1H-pyrazol-3-yl]butanedioate
CAS No.:90460-18-7
Molecular Formula:C15H17N3O4
Molecular Weight:303.318
Hs Code.:
DSSTox Substance ID:DTXSID40535669

Synonyms:90460-18-7;DTXSID40535669;Dimethyl 2-[1-(2-aminophenyl)-1H-pyrazol-3-yl]butanedioate

Suppliers and Price of Dimethyl 2-[1-(2-aminophenyl)-1H-pyrazol-3-yl]butanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Dimethyl 2-[1-(2-aminophenyl)-1H-pyrazol-3-yl]butanedioate

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:303.12190603
Heavy Atom Count:22
Complexity:404

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC(C1=NN(C=C1)C2=CC=CC=C2N)C(=O)OC

Technology Process of Dimethyl 2-[1-(2-aminophenyl)-1H-pyrazol-3-yl]butanedioate

There total 3 articles about Dimethyl 2-[1-(2-aminophenyl)-1H-pyrazol-3-yl]butanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 90460-15-4
dimethyl 2-(pyrazolo<1,2-a>benzotriazol-3-yl)fumarate

: 90460-18-7
2-[1-(2-Amino-phenyl)-1H-pyrazol-3-yl]-succinic acid dimethyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 760 Torr; Ambient temperature;
DOI:10.1021/jo00189a003

Reference yield: 90.0%

: 90481-23-5
dimethyl 2-(pyrazolo<1,2-a>benzotriazol-3-yl)maleate

: 90460-18-7
2-[1-(2-Amino-phenyl)-1H-pyrazol-3-yl]-succinic acid dimethyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 760 Torr; Ambient temperature;
DOI:10.1021/jo00189a003

Reference yield:

: 1738-57-4
Pyrazolobenzo<1,2-a>triazole

: 90460-18-7
2-[1-(2-Amino-phenyl)-1H-pyrazol-3-yl]-succinic acid dimethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 10 percent / methanol / 4 h / Ambient temperature

2: 90 percent / H₂ / Pd/C (10 percent) / ethanol / 760 Torr / Ambient temperature

With hydrogen; palladium on activated charcoal; In methanol; ethanol;
DOI:10.1021/jo00189a003