Carbamic acid, (5-amino-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

Base Information

Chemical Name:Carbamic acid, (5-amino-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester
CAS No.:83269-15-2
Molecular Formula:C16H15 N5 O2
Molecular Weight:309.3226
Hs Code.:
NSC Number:337238
DSSTox Substance ID:DTXSID401003241
Nikkaji Number:J351.935J
Wikidata:Q82997709
ChEMBL ID:CHEMBL104996

Synonyms:83269-15-2;NSC337238;NSC-337238;CHEMBL104996;SCHEMBL13342704;DTXSID401003241;NSC 337238;ethyl N-(5-amino-3-phenyl-pyrido[3,4-b]pyrazin-7-yl)carbamate;Carbamic acid, (5-amino-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester;Ethyl hydrogen (5-amino-3-phenylpyrido[3,4-b]pyrazin-7-yl)carbonimidate;Carbamic acid,5-amino-3-phenyl pyrido[3,4-b]pyrazin-7-yl, ethyl ester, chloroformate [20:7].

Suppliers and Price of Carbamic acid, (5-amino-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of Carbamic acid, (5-amino-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

Chemical Property:

Vapor Pressure:3.61E-10mmHg at 25°C
Boiling Point:501°Cat760mmHg
Flash Point:256.8°C
Density:1.364g/cm³
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:309.12257474
Heavy Atom Count:23
Complexity:402

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)NC1=NC(=C2C(=C1)N=CC(=N2)C3=CC=CC=C3)N

Technology Process of Carbamic acid, (5-amino-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

There total 3 articles about Carbamic acid, (5-amino-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 82585-91-9
ethyl (5-amino-1,2-dihydro-3-phenylpyrido<3,4-b>pyrazin-7-yl)carbamate

: 83269-15-2
ethyl (5-amino-3-phenylpyrido<3,4-b>pyrazin-7-yl)carbamate

Guidance literature:: With potassium permanganate; magnesium sulfate; In acetone; for 2h;
DOI:10.1021/jm00355a018

Reference yield:

: 38359-80-7
ethyl <4,5-diamino-6-<(diphenylmethyl)amino>pyridin-2-yl>carbamate dihydrochloride

: 83269-15-2
ethyl (5-amino-3-phenylpyrido<3,4-b>pyrazin-7-yl)carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: 62 percent / EtONa / ethanol / 1.) RT, 18 h, 2.) reflux, 12 h

2: 97 percent / conc. HCl / 18 h

3: 1.) Me₂S*BH₃, 2.) KMnO₄ / 1.) THF, 20 h, 2.) acetone, 0.8 h

With hydrogenchloride; potassium permanganate; dimethylsulfide borane complex; sodium ethanolate; In ethanol;
DOI:10.1021/jm00173a021

Reference yield:

: 130145-52-7
ethyl <5-<(diphenylmethyl)amino>-1,2-dihydro-2-oxo-3-phenylpyrido<3,4-b>pyrazin-7-yl>carbamate

: 83269-15-2
ethyl (5-amino-3-phenylpyrido<3,4-b>pyrazin-7-yl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / conc. HCl / 18 h

2: 1.) Me₂S*BH₃, 2.) KMnO₄ / 1.) THF, 20 h, 2.) acetone, 0.8 h

With hydrogenchloride; potassium permanganate; dimethylsulfide borane complex;
DOI:10.1021/jm00173a021