6-Hydroxymellein

Base Information

Chemical Name:6-Hydroxymellein
CAS No.:70901-60-9
Molecular Formula:C10H10 O4
Molecular Weight:194.187
Hs Code.:2932209090
UNII:PUH8Z0Q805
DSSTox Substance ID:DTXSID90991190
Nikkaji Number:J500.131E
Wikipedia:6-Hydroxymellein
Wikidata:Q4641539
Metabolomics Workbench ID:50472
Mol file:70901-60-9.mol

Synonyms:3,4-dihydro-6,8-dihydroxy-3-methyl-isocoumarin;3,4-dihydro-6,8-dihydroxy-3-methylisocoumarin;6,8-dihydroxy-3-methyl-3,4-dihydroisocoumarin;6-hydroxy-mellein;6-hydroxymellein

Suppliers and Price of 6-Hydroxymellein

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6-Hydroxymellein

Chemical Property:

Vapor Pressure:1.52E-09mmHg at 25°C
Boiling Point:472.3°C at 760 mmHg
Flash Point:196.6°C
PSA：66.76000
Density:1.38g/cm³
LogP:1.19920
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:194.05790880
Heavy Atom Count:14
Complexity:240

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2=C(C(=CC(=C2)O)O)C(=O)O1
Isomeric SMILES:C[C@@H]1CC2=C(C(=CC(=C2)O)O)C(=O)O1

Technology Process of 6-Hydroxymellein

There total 16 articles about 6-Hydroxymellein which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 1613133-92-8
talapolyester A

: 70901-60-9
(R)-6-hydroxymellein

: 5469-16-9,58081-05-3,131432-37-6,7331-52-4
(3S)-hydroxy-γ-butyrolactone

Guidance literature:: talapolyester A; With sodium hydroxide; at 20 ℃; for 24h;

In toluene; at 130 ℃; for 10h;
DOI:10.1016/j.tet.2014.02.060

Reference yield: 7.8%

: 6,8-dihydroxy-3-methyl-3,4,4a,5,6,7-hexahydro-1H-isochromen-1-one

: (3R,4aR)-8-Hydroxy-3-methyl-3,4,4a,7-tetrahydro-5H-isochromene-1,6-dione

: 70901-60-9
(R)-6-hydroxymellein

: 480-33-1,1200-93-7,17397-85-2,62623-84-1
(R)-(-)-mellein

Guidance literature:: With jones reagent; In acetone; at 0 ℃; for 0.75h;
DOI:10.1016/j.tet.2006.11.068

Reference yield:

: hansforester B

: 625-72-9,26063-00-3,29435-48-1
(R)-3-hydroxybutyric acid

: 70901-60-9
(R)-6-hydroxymellein

Guidance literature:: hansforester B; With sodium hydroxide; at 20 ℃; for 24h;

With toluene-4-sulfonic acid; In benzene; for 0.5h; Reflux;
DOI:10.1039/c8ra08606k