Technology Process of L-Proline, 5-(5-oxohexyl)-1-(phenylmethyl)-, cis-
There total 3 articles about L-Proline, 5-(5-oxohexyl)-1-(phenylmethyl)-, cis- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: LDA / dimethylsulfoxide; tetrahydrofuran / 1 h / 0 °C
2: 93 percent / H2 / 5percent Pt/C / ethyl acetate / 6 h / 2585.7 Torr
3: glacial acetic acid / propan-1-ol; H2O / 4 h / Heating
With
hydrogen; acetic acid; lithium diisopropyl amide;
platinum on activated charcoal;
In
tetrahydrofuran; propan-1-ol; water; dimethyl sulfoxide; ethyl acetate;
DOI:10.1021/ja00328a040
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 93 percent / H2 / 5percent Pt/C / ethyl acetate / 6 h / 2585.7 Torr
2: glacial acetic acid / propan-1-ol; H2O / 4 h / Heating
With
hydrogen; acetic acid;
platinum on activated charcoal;
In
propan-1-ol; water; ethyl acetate;
DOI:10.1021/ja00328a040
- Guidance literature:
-
With
acetic acid;
In
propan-1-ol; water;
for 4h;
Heating;
DOI:10.1021/ja00328a040
