(E)-5-Dodecen-1-ol

Base Information

• Chemical Name: (E)-5-Dodecen-1-ol
• CAS No.: 62936-12-3
• Molecular Formula: C12H24O
• Molecular Weight: 184.3184
• Hs Code.: 2905290000
• DSSTox Substance ID: DTXSID30886516
• Nikkaji Number: J390.926C,J610.279D
• Wikidata: Q82865367
• Metabolomics Workbench ID: 3236
• Mol file: 62936-12-3.mol

Synonyms:(E)-5-Dodecen-1-ol;(E)-dodec-5-en-1-ol;62936-12-3;5E-Dodecen-1-ol;5-Dodecen-1-ol, (5E)-;5-Dodecenol;5-Dodecen-1-ol, (E)-;5-Dodecen-1-ol;(5E)-DODEC-5-EN-1-OL;AI3-37777;5-Dodecen-1-o1, (E)-;trans-5-dodecenol;5-Dodecenol, E;(5E)-5-Dodecen-1-ol;SCHEMBL1300999;SCHEMBL1301591;DTXSID30886516;CHEBI:188421;OTJWLIMIKGBSSN-BQYQJAHWSA-N;LMFA05000146

Chemical Property of (E)-5-Dodecen-1-ol

Chemical Property:

• Vapor Pressure: 0.000919mmHg at 25°C
• Melting Point: 77.27°C (estimate)
• Refractive Index: 1.4531 (estimate)
• Boiling Point: 270.1°Cat760mmHg
• Flash Point: 98.8°C
• PSA: 20.23000
• Density: 0.846g/cm³
• LogP: 3.67560
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 9
• Exact Mass: 184.182715385
• Heavy Atom Count: 13
• Complexity: 108

Purity/Quality:

99% ^*data from raw suppliers

(E)-5-DODECEN-1-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCC=CCCCCO
• Isomeric SMILES: CCCCCC/C=C/CCCCO

Technology Process of (E)-5-Dodecen-1-ol

There total 5 articles about (E)-5-Dodecen-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

dodec-5E-enoic acid (5684-80-0) + (E)-Dodec-5-enoic acid butyl ester (139448-71-8) → dodec-5E-en-1-ol (62936-12-3)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 3h; Heating;

DOI:10.1007/BF00629846

Reference yield:

(3E)-dec-3-enoic acid (2430-93-5,15469-77-9,53678-20-9) → dodec-5E-en-1-ol (62936-12-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 65 percent / LiAlH₄ / diethyl ether / 3 h / Heating

2: 67 percent / PBr₃, pyridine / diethyl ether / 1. -5 deg C to 0 deg C, 1 day, 2. reflux, 2 h

4: 72 percent / LiAlH₄ / diethyl ether / 3 h / Heating

With pyridine; lithium aluminium tetrahydride; phosphorus tribromide; In diethyl ether;

DOI:10.1007/BF00629846

Reference yield:

Octanal (124-13-0) → dodec-5E-en-1-ol (62936-12-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 68 percent / piperidine / xylene / 4 h / Heating

2: 65 percent / LiAlH₄ / diethyl ether / 3 h / Heating

3: 67 percent / PBr₃, pyridine / diethyl ether / 1. -5 deg C to 0 deg C, 1 day, 2. reflux, 2 h

5: 72 percent / LiAlH₄ / diethyl ether / 3 h / Heating

With piperidine; pyridine; lithium aluminium tetrahydride; phosphorus tribromide; In diethyl ether; xylene;

DOI:10.1007/BF00629846

upstream raw materials:

dodec-5E-enoic acid

(E)-Dodec-5-enoic acid butyl ester

(3E)-dec-3-enoic acid

Octanal