Technology Process of 6-Quinoxalinecarboxylic acid, 3-methyl-2-phenyl-
There total 10 articles about 6-Quinoxalinecarboxylic acid, 3-methyl-2-phenyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
water; lithium hydroxide;
In
1,4-dioxane;
for 1h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: ammonium chloride; iron / methanol / 2 h / Reflux
2: 2,3-dicyano-5,6-dichloro-p-benzoquinone / 1,4-dioxane / 3 h / 20 °C
3: phosphorus pentachloride / acetonitrile / 5 h / Reflux
4: XPhos; tris-(dibenzylideneacetone)dipalladium(0) / 1,4-dioxane / 6 h / 100 °C / Sealed tube; Inert atmosphere
5: water; lithium hydroxide / 1,4-dioxane / 1 h / Reflux
With
tris-(dibenzylideneacetone)dipalladium(0); phosphorus pentachloride; water; iron; ammonium chloride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hydroxide; XPhos;
In
1,4-dioxane; methanol; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / 1,4-dioxane / 3 h / 20 °C
2: phosphorus pentachloride / acetonitrile / 5 h / Reflux
3: XPhos; tris-(dibenzylideneacetone)dipalladium(0) / 1,4-dioxane / 6 h / 100 °C / Sealed tube; Inert atmosphere
4: water; lithium hydroxide / 1,4-dioxane / 1 h / Reflux
With
tris-(dibenzylideneacetone)dipalladium(0); phosphorus pentachloride; water; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hydroxide; XPhos;
In
1,4-dioxane; acetonitrile;
