2-Pyridinecarboxylic acid, 5-[acetyl[(4-methylphenyl)sulfonyl]amino]-, ethyl ester

Base Information

Chemical Name:2-Pyridinecarboxylic acid, 5-[acetyl[(4-methylphenyl)sulfonyl]amino]-, ethyl ester
CAS No.:90866-95-8
Molecular Formula:C17H18N2O5S
Molecular Weight:362.406
Hs Code.:

Synonyms:

Suppliers and Price of 2-Pyridinecarboxylic acid, 5-[acetyl[(4-methylphenyl)sulfonyl]amino]-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Pyridinecarboxylic acid, 5-[acetyl[(4-methylphenyl)sulfonyl]amino]-, ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Pyridinecarboxylic acid, 5-[acetyl[(4-methylphenyl)sulfonyl]amino]-, ethyl ester

There total 6 articles about 2-Pyridinecarboxylic acid, 5-[acetyl[(4-methylphenyl)sulfonyl]amino]-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 108-24-7
acetic anhydride

: 90866-93-6
ethyl 5-(p-toluenesulfonamido)picolinate

: 90866-94-7
ethyl N-acetyl-5-(p-toluenesulfonamido)pipecolate

: 90866-96-9
ethyl N-ethyl-5-(p-toluenesulfonamido)pipecolate

: 90866-95-8
ethyl 5-(N-acetyl-p-toluenesulfonamido)picolinate

Guidance literature:: With hydrogen; platinum(IV) oxide; In acetic acid; Yields of byproduct given;
DOI:10.1021/jo00194a002

Reference yield:

: 21203-68-9
2-methyl-5-nitropyridine

: 90866-95-8
ethyl 5-(N-acetyl-p-toluenesulfonamido)picolinate

Guidance literature:: Multi-step reaction with 5 steps

1: 83 percent / chromium trioxide/conc. H₂SO₄ / Ambient temperature

2: 97 percent / Dowex 50W / benzene

3: H₂ / 10percent Pd-C / ethanol / 7 h / 2280 Torr

4: pyridine / 1) 10 min. RT, 2) steam bath, 15 min.

5: H₂ / PtO₂ / acetic acid

With pyridine; chromium(VI) oxide; sulfuric acid; hydrogen; platinum(IV) oxide; palladium on activated charcoal; Dowex 50W; In ethanol; acetic acid; benzene;
DOI:10.1021/jo00194a002

Reference yield:

: 4548-45-2
2-chloro-5-nitropyridine

: 90866-95-8
ethyl 5-(N-acetyl-p-toluenesulfonamido)picolinate

Guidance literature:: Multi-step reaction with 6 steps

1: 55 percent

2: 83 percent / chromium trioxide/conc. H₂SO₄ / Ambient temperature

3: 97 percent / Dowex 50W / benzene

4: H₂ / 10percent Pd-C / ethanol / 7 h / 2280 Torr

5: pyridine / 1) 10 min. RT, 2) steam bath, 15 min.

6: H₂ / PtO₂ / acetic acid

With pyridine; chromium(VI) oxide; sulfuric acid; hydrogen; platinum(IV) oxide; palladium on activated charcoal; Dowex 50W; In ethanol; acetic acid; benzene;
DOI:10.1021/jo00194a002